Diagnostic Testing for Crimean-Congo Hemorrhagic Fever

J Clin Microbiol. 2020 Mar 25;58(4):e01580-19. doi: 10.1128/JCM.01580-19. Print 2020 Mar 25.

Abstract

Crimean-Congo hemorrhagic fever is the most geographically widespread tick-borne virus, with infection resulting in mortality in up to 30% of cases. Clinical diagnosis alone is difficult due to the nonspecific nature of symptoms; therefore, laboratory diagnostics should be utilized for patients with residence in or travel to regions of endemicity in whom the disease is suspected. This minireview provides an overview of laboratory tests available for Crimean-Congo hemorrhagic fever (CCHF) and their utility in diagnosis with a focus on diagnosing CCHF in humans.

Keywords: Crimean-Congo hemorrhagic fever virus.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Diagnostic Techniques and Procedures
  • Diagnostic Tests, Routine
  • Hemorrhagic Fever Virus, Crimean-Congo*
  • Hemorrhagic Fever, Crimean* / diagnosis
  • Humans
  • Travel