Abstract
We describe a hypervirulent clone of group B Streptococcus serotype III, subtype 4, sequence type 283, that caused invasive disease with a predilection for meningitis in Hong Kong during 1993-2012. The organism is associated with high mortality and increased summer prevalence and is linked to diseased fish from freshwater fish farms.
Keywords:
Group B Streptococcus; Hong Kong; bacteria; clone; fish disease; hypervirulent; meningitis; newborns; serotype III-4/ST283; zoonoses.
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Animals
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Electrophoresis, Gel, Pulsed-Field
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Female
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Fish Diseases / microbiology
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Hong Kong / epidemiology
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Humans
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Humidity
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Infant, Newborn
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Male
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Middle Aged
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Pregnancy
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Seasons
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Serotyping
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Streptococcal Infections / epidemiology
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Streptococcal Infections / microbiology*
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Streptococcal Infections / veterinary
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Streptococcus agalactiae / classification*
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Streptococcus agalactiae / genetics
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Streptococcus agalactiae / isolation & purification
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Streptococcus agalactiae / pathogenicity
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Temperature
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Virulence
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Young Adult