Hairy math: insights into hair-follicle spacing and orientation

Cell. 2007 Jan 12;128(1):17-20. doi: 10.1016/j.cell.2006.12.020.

Abstract

Hair follicles in the skin have a characteristic spacing and orientation. Two recent papers (Sick et al., 2006 and Wang et al., 2006) report the use of contrasting mathematical models and experimental manipulations to gain insight into the mechanisms underlying patterns of hair-follicle distribution and orientation.

MeSH terms

  • Animals
  • Body Patterning*
  • Hair Follicle / anatomy & histology
  • Hair Follicle / cytology*
  • Hair Follicle / growth & development*
  • Mice
  • Models, Biological
  • Signal Transduction
  • Wnt Proteins / metabolism
  • beta Catenin / metabolism

Substances

  • Wnt Proteins
  • beta Catenin