This study investigated the connection between wisdom as a body of expert knowledge about the meaning and conduct of life and indicators of affective, motivational, and interpersonal functioning. Structural equation analyses showed that individuals higher on wisdom-related knowledge reported (a) higher affective involvement combined with lower negative and pleasant feelings, (b) a value orientation that focused conjointly on other-enhancing values and personal growth combined with a lesser tendency toward values revolving around a pleasurable life, and (c) a preference for cooperative conflict management strategies combined with a lower tendency to adopt submissive, avoidant, or dominant strategies. These findings corroborate the theoretical notion that wisdom involves affective modulation and complexity rather than the predominant seeking of pleasure and also a joint motivational commitment to developing the potential of oneself and that of others.