Glycerophosphodiester phosphodiesterase gene (glpQ) of Borrelia lonestari identified as a target for differentiating Borrelia species associated with hard ticks (Acari:Ixodidae)

Rendi Murphree Bacon; Mark A Pilgard; Barbara J B Johnson; Sandra J Raffel; Tom G Schwan

doi:10.1128/JCM.42.5.2326-2328.2004

Glycerophosphodiester phosphodiesterase gene (glpQ) of Borrelia lonestari identified as a target for differentiating Borrelia species associated with hard ticks (Acari:Ixodidae)

J Clin Microbiol. 2004 May;42(5):2326-8. doi: 10.1128/JCM.42.5.2326-2328.2004.

Authors

Rendi Murphree Bacon¹, Mark A Pilgard, Barbara J B Johnson, Sandra J Raffel, Tom G Schwan

Affiliation

¹ Bacterial Zoonoses Branch, Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80521, USA. [email protected]

Abstract

A glpQ ortholog was identified in DNA from Borrelia lonestari-positive Amblyomma americanum, providing further evidence that B. lonestari is more closely related to the relapsing fever group spirochetes than to borreliae that cause Lyme disease. This finding provides a basis for developing diagnostic assays to differentiate species of borrelia transmitted by hard ticks.

Publication types

Comparative Study

MeSH terms

Amino Acid Sequence
Animals
Bacterial Proteins / genetics*
Bacterial Typing Techniques
Base Sequence
Borrelia / classification
Borrelia / enzymology*
Borrelia / genetics*
Borrelia Infections / diagnosis
Borrelia Infections / microbiology
DNA Primers / genetics
DNA, Bacterial / genetics
Genes, Bacterial*
Humans
Ixodidae / microbiology*
Molecular Sequence Data
Phosphoric Diester Hydrolases / genetics*
Sequence Homology, Amino Acid
Species Specificity

Substances

Bacterial Proteins
DNA Primers
DNA, Bacterial
Phosphoric Diester Hydrolases
glpQ protein, Bacteria

Associated data

GENBANK/AY368275
GENBANK/AY368276