Cromossoma 10
Aspeto
Este artigo não cita fontes confiáveis. (Fevereiro de 2020) |
![](http://upload.wikimedia.org/wikipedia/commons/6/60/Human_male_karyotpe_high_resolution_-_Chromosome_10_cropped.png)
![](http://upload.wikimedia.org/wikipedia/commons/thumb/2/24/Chromosome_10.svg/125px-Chromosome_10.svg.png)
O cromossoma 10 é um dos 23 pares de cromossomas do cariótipo humano.
Genes
[editar | editar código-fonte]- ALOX5: Arachidonate 5-Lipoxygenase (processes essential fatty acids to leukotrienes, which are important agents in the inflammatory response; also facilitates development and maintenance of cancer stem cells, slow-dividing cells thought to give rise to a variety of cancers, including leukemia);
Gene | Descrição |
---|---|
CDH23 | cadherin-like 23 |
CXCL12 | chemokine (C-X-C motif) ligand 12, SDF-1, scyb12 |
EGR2 | early growth response 2 (Krox-20 homolog, Drosophila) |
ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 |
FGFR2 | fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) |
HELLS | Lymphoid-specific helicase |
PCBD1 | 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) |
PCDH15 | protocadherin 15 |
PTEN gene | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) |
RET | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) |
UROS | uroporphyrinogen III synthase (congenital erythropoietic porphyria) |
Doenças
[editar | editar código-fonte]O cromossomos é constituído por 24 genes colaterais