Nanoparticles are designed to deliver therapeutics and diagnostics selectively to tumors. Their s... more Nanoparticles are designed to deliver therapeutics and diagnostics selectively to tumors. Their size, shape, charge, material, coating, and cargo determine their individual functionalities. A systems approach could help predict the behavior of trillions of nanoparticles interacting in complex tumor environments. Engineering these nanosystems may lead to biomimetic strategies where interactions between nanoparticles and their environment give rise to cooperative behaviors typically seen in natural self-organized systems. Examples include nanoparticles that communicate the location of a tumor to amplify tumor homing or self-assemble and disassemble to optimize nanoparticle transport. The challenge is to discover which nanoparticle designs lead to a desired system behavior. To this end, novel nanomaterials, deep understanding of biology, and computational tools are emerging as the next frontier.
Swarms of flying robots can be used in disaster areas to autonomously create communication networ... more Swarms of flying robots can be used in disaster areas to autonomously create communication networks for rescuers and victims. Flying robots have the advantage of rapidly overcoming difficult terrain and providing unobstructed wireless communication. To allow for a swarm composed of cheap, transportable and robust robots, we avoid using positioning sensors which typically depend on the environment (GPS, cameras) or are expensive and heavy (lasers, radars). Instead, robot behaviors depend on local ...
Nanoparticles are designed to deliver therapeutics and diagnostics selectively to tumors. Their s... more Nanoparticles are designed to deliver therapeutics and diagnostics selectively to tumors. Their size, shape, charge, material, coating, and cargo determine their individual functionalities. A systems approach could help predict the behavior of trillions of nanoparticles interacting in complex tumor environments. Engineering these nanosystems may lead to biomimetic strategies where interactions between nanoparticles and their environment give rise to cooperative behaviors typically seen in natural self-organized systems. Examples include nanoparticles that communicate the location of a tumor to amplify tumor homing or self-assemble and disassemble to optimize nanoparticle transport. The challenge is to discover which nanoparticle designs lead to a desired system behavior. To this end, novel nanomaterials, deep understanding of biology, and computational tools are emerging as the next frontier.
Swarms of flying robots can be used in disaster areas to autonomously create communication networ... more Swarms of flying robots can be used in disaster areas to autonomously create communication networks for rescuers and victims. Flying robots have the advantage of rapidly overcoming difficult terrain and providing unobstructed wireless communication. To allow for a swarm composed of cheap, transportable and robust robots, we avoid using positioning sensors which typically depend on the environment (GPS, cameras) or are expensive and heavy (lasers, radars). Instead, robot behaviors depend on local ...
Uploads
Papers