The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for pre... more The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for predicting post-operative forced expiratory volume in 1 second (FEV1) values for lung resection candidates; this new model will be based on data derived from a thoracic CT scan with injection of contrast media. This registration includes information contained in the eCRF.
Additional file 3. Definition of the Central Sleep Apnea Group, the Obstructive Sleep Apnea group... more Additional file 3. Definition of the Central Sleep Apnea Group, the Obstructive Sleep Apnea group, and the Treatment Emergent Central Sleep Apnea Group.
Additional file 1: Supplemental Digital Content – Table 1. Definition of hospital stays in resusc... more Additional file 1: Supplemental Digital Content – Table 1. Definition of hospital stays in resuscitation / ICUs for COPD exacerbation based on ICD-10 codes.
Additional file 4: Supplemental Digital Content – Table 4. PDs of deceased patients in the propen... more Additional file 4: Supplemental Digital Content – Table 4. PDs of deceased patients in the propensity score groups.
Additional file 5: Supplemental - Table 5. Practice Survey among intensivists about their use of ... more Additional file 5: Supplemental - Table 5. Practice Survey among intensivists about their use of bronchoscopy during an acute exacerbation of COPD.
Additional file 3: Supplemental Digital Content – Table 3. PDs of patients in the groups derived ... more Additional file 3: Supplemental Digital Content – Table 3. PDs of patients in the groups derived from propensity scoring.
Additional file 5. Date of the last cardiological consultation depending on the year of ASV initi... more Additional file 5. Date of the last cardiological consultation depending on the year of ASV initiation (pâ =â 0.19).
ObjectivesPresently, those outcomes that should be prioritised for chronic obstructive pulmonary ... more ObjectivesPresently, those outcomes that should be prioritised for chronic obstructive pulmonary disease (COPD) exacerbation studies remain unclear. In order to coordinate multicentre studies on eosinophilia-driven corticosteroid therapy for patients hospitalised for acute exacerbation of COPD (AECOPD), we aimed to find consensus among experts in the domain regarding the prioritisation of outcomes.DesignA modified Delphi study was proposed to recognised COPD experts. Two brainstorming questionnaires were used to collect potential outcomes. Four subsequent rounds of questionnaires were used to rank items according to a six-point Likert scale for their importance in the protocol, as well as for being the primary outcome. Priority outcome criteria were predefined as those for which ≥70% of experts indicated that the outcome was essential for interpreting study results.SettingCOPD exacerbation management in France.Participants34 experts recommended by the French Language Pulmonology Soc...
Background Whereas telemedicine usage is growing, the only clinical algorithm for Continuous Posi... more Background Whereas telemedicine usage is growing, the only clinical algorithm for Continuous Positive Airway Pressure (CPAP) adherence management is that stipulated by the 2013 American Thoracic Society (ATS). The capacity of the latter to predict non-adherence in long-term CPAP-treated patients has not been validated. Methods Patients from the prospective real-life InterfaceVent study (NCT03013283, study conducted in an adult cohort undergoing at least 3 months of CPAP) and eligible for ATS algorithm usage were analysed. The residual device Apnea–Hypopnea-Index (AHIflow) and High Large Leak (HLL) thresholds proposed in the ATS algorithm were evaluated for predicting adherence (i.e. AHIflow > 10/h, HLLs 95th > 24 L/min for ResMed® devices and ResMed® nasal mask, HLLs 95th > 36 l/min for ResMed® devices and ResMed® oronasal masks, HLLs > 1 h for Philips® devices and HHLs > 60 l/min for Fisher & Paykel® devices). Adherence was defined according to the 2013 ATS algorithm...
Pulmonary arterial hypertension (PAH) is a rare and life-threatening disease well-marked by under... more Pulmonary arterial hypertension (PAH) is a rare and life-threatening disease well-marked by under diagnosis, delayed diagnosis and atypical treatments. Few data are available on the quality of life (QoL) and psychosocial characteristics of patients with PAH. Our aim is to describe the impact of psychological factors on the health-related quality of life (HRQoL) of treated PAH patients in a cross-sectional study. Consecutive patients presenting at our Competency Centre for PAH were recruited. The aetiology, New York Heart Association (NYHA) stage, haemodynamics, 6-min walk distance (6MWD), delta SPO2 (Pulse oximeter oxygen saturation; baseline lowest value during 6-min walk test (6MWT), current treatments and psychological history were recorded. HRQoL, anxiety, depression and coping strategies were explored using self-administered questionnaires (SF-36, HADS, STAI-Y, CHIP and WCC). A total of 55 patients were included. The HRQoL of PAH patients was poor with altered results on severa...
Background Predicting fluid responsiveness remains a difficult question in hemodynamically unstab... more Background Predicting fluid responsiveness remains a difficult question in hemodynamically unstable patients. The author's objective was to test whether noninvasive assessment by transthoracic echocardiography of subaortic velocity time index (VTI) variation after a low volume of fluid infusion (100 ml hydroxyethyl starch) can predict fluid responsiveness. Methods Thirty-nine critically ill ventilated and sedated patients with acute circulatory failure were prospectively studied. Subaortic VTI was measured by transthoracic echocardiography before fluid infusion (baseline), after 100 ml hydroxyethyl starch infusion over 1 min, and after an additional infusion of 400 ml hydroxyethyl starch over 14 min. The authors measured the variation of VTI after 100 ml fluid (ΔVTI 100) for each patient. Receiver operating characteristic curves were generated for (ΔVTI 100). When available, receiver operating characteristic curves also were generated for pulse pressure variation and central ven...
The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for pre... more The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for predicting post-operative forced expiratory volume in 1 second (FEV1) values for lung resection candidates; this new model will be based on data derived from a thoracic CT scan with injection of contrast media. This registration includes information contained in the eCRF.
Additional file 3. Definition of the Central Sleep Apnea Group, the Obstructive Sleep Apnea group... more Additional file 3. Definition of the Central Sleep Apnea Group, the Obstructive Sleep Apnea group, and the Treatment Emergent Central Sleep Apnea Group.
Additional file 1: Supplemental Digital Content – Table 1. Definition of hospital stays in resusc... more Additional file 1: Supplemental Digital Content – Table 1. Definition of hospital stays in resuscitation / ICUs for COPD exacerbation based on ICD-10 codes.
Additional file 4: Supplemental Digital Content – Table 4. PDs of deceased patients in the propen... more Additional file 4: Supplemental Digital Content – Table 4. PDs of deceased patients in the propensity score groups.
Additional file 5: Supplemental - Table 5. Practice Survey among intensivists about their use of ... more Additional file 5: Supplemental - Table 5. Practice Survey among intensivists about their use of bronchoscopy during an acute exacerbation of COPD.
Additional file 3: Supplemental Digital Content – Table 3. PDs of patients in the groups derived ... more Additional file 3: Supplemental Digital Content – Table 3. PDs of patients in the groups derived from propensity scoring.
Additional file 5. Date of the last cardiological consultation depending on the year of ASV initi... more Additional file 5. Date of the last cardiological consultation depending on the year of ASV initiation (pâ =â 0.19).
ObjectivesPresently, those outcomes that should be prioritised for chronic obstructive pulmonary ... more ObjectivesPresently, those outcomes that should be prioritised for chronic obstructive pulmonary disease (COPD) exacerbation studies remain unclear. In order to coordinate multicentre studies on eosinophilia-driven corticosteroid therapy for patients hospitalised for acute exacerbation of COPD (AECOPD), we aimed to find consensus among experts in the domain regarding the prioritisation of outcomes.DesignA modified Delphi study was proposed to recognised COPD experts. Two brainstorming questionnaires were used to collect potential outcomes. Four subsequent rounds of questionnaires were used to rank items according to a six-point Likert scale for their importance in the protocol, as well as for being the primary outcome. Priority outcome criteria were predefined as those for which ≥70% of experts indicated that the outcome was essential for interpreting study results.SettingCOPD exacerbation management in France.Participants34 experts recommended by the French Language Pulmonology Soc...
Background Whereas telemedicine usage is growing, the only clinical algorithm for Continuous Posi... more Background Whereas telemedicine usage is growing, the only clinical algorithm for Continuous Positive Airway Pressure (CPAP) adherence management is that stipulated by the 2013 American Thoracic Society (ATS). The capacity of the latter to predict non-adherence in long-term CPAP-treated patients has not been validated. Methods Patients from the prospective real-life InterfaceVent study (NCT03013283, study conducted in an adult cohort undergoing at least 3 months of CPAP) and eligible for ATS algorithm usage were analysed. The residual device Apnea–Hypopnea-Index (AHIflow) and High Large Leak (HLL) thresholds proposed in the ATS algorithm were evaluated for predicting adherence (i.e. AHIflow > 10/h, HLLs 95th > 24 L/min for ResMed® devices and ResMed® nasal mask, HLLs 95th > 36 l/min for ResMed® devices and ResMed® oronasal masks, HLLs > 1 h for Philips® devices and HHLs > 60 l/min for Fisher & Paykel® devices). Adherence was defined according to the 2013 ATS algorithm...
Pulmonary arterial hypertension (PAH) is a rare and life-threatening disease well-marked by under... more Pulmonary arterial hypertension (PAH) is a rare and life-threatening disease well-marked by under diagnosis, delayed diagnosis and atypical treatments. Few data are available on the quality of life (QoL) and psychosocial characteristics of patients with PAH. Our aim is to describe the impact of psychological factors on the health-related quality of life (HRQoL) of treated PAH patients in a cross-sectional study. Consecutive patients presenting at our Competency Centre for PAH were recruited. The aetiology, New York Heart Association (NYHA) stage, haemodynamics, 6-min walk distance (6MWD), delta SPO2 (Pulse oximeter oxygen saturation; baseline lowest value during 6-min walk test (6MWT), current treatments and psychological history were recorded. HRQoL, anxiety, depression and coping strategies were explored using self-administered questionnaires (SF-36, HADS, STAI-Y, CHIP and WCC). A total of 55 patients were included. The HRQoL of PAH patients was poor with altered results on severa...
Background Predicting fluid responsiveness remains a difficult question in hemodynamically unstab... more Background Predicting fluid responsiveness remains a difficult question in hemodynamically unstable patients. The author's objective was to test whether noninvasive assessment by transthoracic echocardiography of subaortic velocity time index (VTI) variation after a low volume of fluid infusion (100 ml hydroxyethyl starch) can predict fluid responsiveness. Methods Thirty-nine critically ill ventilated and sedated patients with acute circulatory failure were prospectively studied. Subaortic VTI was measured by transthoracic echocardiography before fluid infusion (baseline), after 100 ml hydroxyethyl starch infusion over 1 min, and after an additional infusion of 400 ml hydroxyethyl starch over 14 min. The authors measured the variation of VTI after 100 ml fluid (ΔVTI 100) for each patient. Receiver operating characteristic curves were generated for (ΔVTI 100). When available, receiver operating characteristic curves also were generated for pulse pressure variation and central ven...
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