Papers by Sofa Dewi Alfian
BMC medical informatics and decision making, May 21, 2024
Current psychology, Apr 16, 2024
Vascular Health and Risk Management, Nov 30, 2023
BMC Medical Education, Oct 25, 2023
Pharmacy Practice (internet), Oct 4, 2023
Scientific Reports
The prevalence of multimorbidity tends to increase with age, but it is now also reported in the m... more The prevalence of multimorbidity tends to increase with age, but it is now also reported in the middle-aged population, which has a negative impact on healthcare systems and health outcomes. This study aims to analyze the patterns and factors associated with multimorbidity in Indonesia. This national cross-sectional population-based survey used publicly available data from the Indonesian Family Life Survey (IFLS-5) for 2014 among middle-aged (40–59 years old) and elderly (≥ 60 years old) respondents. Information on all chronic diseases was assessed using a self-reported questionnaire. Sociodemographic and health-related behavioral factors were obtained from self-reported data. Binary logistic regression analysis was used to identify the factors associated with multimorbidity. Adjusted odds ratios (AORs) with 95% confidence intervals (CIs) were reported. The study recruited 11,867 respondents. The prevalence of multimorbidity was 18.6% (95% CI 17.9–19.3) with which 15.6% among middle...
Infection and Drug Resistance, Jun 1, 2023
Medicine, Jul 29, 2022
The number of mental disorders has been increasing but has yet to receive sufficient attention. I... more The number of mental disorders has been increasing but has yet to receive sufficient attention. In particular, healthcare students and professionals tend to have high stress burden. Finding the root cause of psychological distress is important to formulate a method for early detection and prevention. The association of brain-derived neurotrophic factor val66met polymorphism to neuropsychiatric disorders has been widely studied. To study the interplay between brain-derived neurotrophic factor val66met polymorphism and sociodemographic factors in the pathogenesis of psychological distress among Indonesian Pharmacy students. Level of psychological distress and sociodemographic profiling was collected by using the Kessler Psychological Distress Scale and sociodemographic questionnaires, respectively. Genotyping was performed using polymerase chain reaction-amplified refractory mutation system. Pearson’s chi square and binomial logistic tests were used to evaluate the correlation. This study recruited 148 participants. The psychological distress levels of the participants were well (27.03%), mild (37.16%), moderate (25.00%), and severe (10.81%). Genotypic distributions were AA (25.67%), GA (50.68%), and GG (23.65%). No statistical significance between genotype and psychological distress was found in the study (P= .076). The sociodemographic factors also showed non significance, except for the source of tuition fee among women students (P= .049). Psychological distress is not affected by genotypic and sociodemographic factors. Further confirmatory research with larger and broader populations is required.
Biomedicines, Jun 22, 2022
Indonesian Journal of Clinical Pharmacy, Mar 1, 2017
Skizofrenia merupakan salah satu gangguan jiwa dengan biaya tinggi dan risiko morbiditas seumur h... more Skizofrenia merupakan salah satu gangguan jiwa dengan biaya tinggi dan risiko morbiditas seumur hidup. Studi farmakoekonomi pada pasien skizofrenia perlu dilakukan untuk mengetahui efisiensi pemilihan kombinasi antipsikotik. Penelitian ini bertujuan untuk menganalisis efektivitas biaya ( cost-effectiveness ) penggunaan kombinasi antipsikotik klozapin-haloperidol dan klozapin-risperidon pada pasien skizofrenia rawat inap di Rumah Sakit Jiwa Provinsi Jawa Barat tahun 2012–2013. Pengumpulan data dilakukan secara retrospektif dari rekam medis pasien yang meliputi komponen biaya langsung, antara lain biaya terapi antipsikotik, biaya penunjang, biaya tindakan medis, biaya rawat inap, dan biaya administrasi. Rata-rata rasio efektivitas biaya pada kombinasi antipsikotik klozapin-haloperidol sebesar Rp126.898/hari sedangkan pada kombinasi klozapin-risperidon sebesar Rp132.781/hari. Dengan mempertimbangkan waktu rawat inap sebagai efektivitas terapi, kombinasi antipsikotik klozapin-haloperidol lebih cost-effective dibandingkan klozapin-risperdion.
Frontiers in Pharmacology, May 5, 2021
Telemedicine Journal and E-health, Feb 7, 2023
Indonesian Journal of Clinical Pharmacy, Dec 17, 2012
Penyakit infeksi masih merupakan penyakit utama yang paling banyak terjadi di negara berkembang s... more Penyakit infeksi masih merupakan penyakit utama yang paling banyak terjadi di negara berkembang seperti Indonesia. Salah satu tempat pelayanan kesehatan yang banyak mendistribusikan antibiotik adalah apotek. Oleh karena itu, studi penggunaan antibiotik di apotek sebagai salah satu komunitas farmasi sangat diperlukan. Tujuan penelitian ini adalah untuk mengetahui profil penggunaan antibiotik antituberkulosis di Apotek di Kota Bandung tahun 2008−2010. Penelitian ini merupakan penelitian observasional dengan pengambilan data secara retrospektif. Penelitian ini dilakukan dengan menggunakan metode Anatomical Therapeutic Chemical/ Defined Daily Dose (ATC/DDD) dan Drug Utilization 90% (DU90%). Hasil penelitian menunjukkan bahwa total penggunaan antibiotik untuk terapi tuberkulosis mengalami penurunan. Nilai DDD/1000 KPRJ tahun 2008, 2009, dan 2010 berturut-turut sebesar 1559,026; 1484,936; dan 1048,111. Selama periode 2008−2010, tingkat penurunan pada tahun 2009 tidak terlalu signifikan, yaitu sebesar 17.783 DDD/1000 Kunjungan Pasien Rawat Jalan (KPRJ), tetapi pada tahun 2010 penurunannya sangat signifikan sebesar 169.416 DDD/1000 KPRJ. Penelitian menyimpulkan bahwa total penggunaan antibiotik antituberkulosis di Apotek di Kota Bandung periode 2008−2010 cenderung mengalami penurunan. Kata kunci: Antibiotik, farmasi, ATC/DDD ( Anatomical Therapeutic Chemical/Defined Daily Dose ), Drug Utilization 90% (DU90%), infeksi Profile of Antituberculosis Use in Community Pharmacist of Bandung City 2008–2010 Abstract Infectious disease is still a major disease in developing countries such as in Indonesia. As one of the healthcare providers which has privilege to distribute antibiotics, it is very important to control the use of antibiotics in pharmacy. The aim of this study is to conduct a profile of anti-tuberculosis use, in all pharmacies in Bandung during the period from 2008–2010. This study was performed using an observational method and retrospective approach. In this study we applied the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) and Drug Utilization 90 % (DU90%) method. The result showed that the use of anti-tuberculosis tends to decrease. During the period from 2008 to 2010, the use of antituberculosis decreased by 17,783 and 169,416 DDD/1000 inhabitants in 2009 and 2010, respectively. It can be concluded that the totaluse of anti-tuberculosis in all pharmacies in Bandung during the period from 2008 to 2010 tends to decrease. Key words: Antibiotic, pharmacy, ATC/DDD (Anatomical Therapeutic Chemical/Defined Daily Dose), Drug Utilization 90% (DU90%), infection
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Nov 1, 2019
Biomedicines, Jan 26, 2023
Journal of Medical Internet Research, Feb 23, 2022
Frontiers in Public Health, Jan 25, 2023
Frontiers in Pharmacology, Sep 26, 2022
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Papers by Sofa Dewi Alfian