Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2013
We report a case of refractory heparin-induced thrombocytopenia with thrombosis (HITT) with prolo... more We report a case of refractory heparin-induced thrombocytopenia with thrombosis (HITT) with prolonged thrombocytopenia and multiple thrombotic complications that failed to improve despite aggressive treatment. A 60 year old female with a prior history of venous thromboembolism was admitted with an acute pulmonary embolism, and developed HITT after several days on heparin therapy. She suffered multiple complications including bilateral venous limb gangrene, acute renal failure, and refractory thrombocytopenia, leading us to use multimodality therapy including therapeutic plasma exchange (TPE) and rituximab immunosuppression. The patient had transient improvements in her thrombocytopenia with TPE, and rituximab was added in an attempt to reduce antibody production. She eventually required bilateral limb amputation, and only after removal of the gangrenous limbs did her platelet count show sustained improvement. We discuss the possible contribution of infection to her prolonged course.
The aim of this study was to identify and rank factors affecting AIDS prevention using multiple a... more The aim of this study was to identify and rank factors affecting AIDS prevention using multiple attribute decision making (MADM) as well as group decision making. At first, factors affecting AIDS prevention were extracted from related literatures. Furthermore, 20 identified factors were submitted to 18 health experts and policy makers who compose a Delphi group in order to be classified and summarized. Finally, 12 factors were selected based on average and standard deviation in two rounds. Then, causal relations between the factors and their network structure were identified using DEMATEL. Finally, ANP was employed to determine the weight of factors and to rank them using Super Decisions. This paper ranked simultaneously the socio-cultural and hygienic factors of AIDS control for the first time. The interaction between a factor and other factors in the same group, or other groups, was also evaluated. Data analysis showed that in ANP-based AIDS prevention and control, educating and p...
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2013
We report a case of refractory heparin-induced thrombocytopenia with thrombosis (HITT) with prolo... more We report a case of refractory heparin-induced thrombocytopenia with thrombosis (HITT) with prolonged thrombocytopenia and multiple thrombotic complications that failed to improve despite aggressive treatment. A 60 year old female with a prior history of venous thromboembolism was admitted with an acute pulmonary embolism, and developed HITT after several days on heparin therapy. She suffered multiple complications including bilateral venous limb gangrene, acute renal failure, and refractory thrombocytopenia, leading us to use multimodality therapy including therapeutic plasma exchange (TPE) and rituximab immunosuppression. The patient had transient improvements in her thrombocytopenia with TPE, and rituximab was added in an attempt to reduce antibody production. She eventually required bilateral limb amputation, and only after removal of the gangrenous limbs did her platelet count show sustained improvement. We discuss the possible contribution of infection to her prolonged course.
The aim of this study was to identify and rank factors affecting AIDS prevention using multiple a... more The aim of this study was to identify and rank factors affecting AIDS prevention using multiple attribute decision making (MADM) as well as group decision making. At first, factors affecting AIDS prevention were extracted from related literatures. Furthermore, 20 identified factors were submitted to 18 health experts and policy makers who compose a Delphi group in order to be classified and summarized. Finally, 12 factors were selected based on average and standard deviation in two rounds. Then, causal relations between the factors and their network structure were identified using DEMATEL. Finally, ANP was employed to determine the weight of factors and to rank them using Super Decisions. This paper ranked simultaneously the socio-cultural and hygienic factors of AIDS control for the first time. The interaction between a factor and other factors in the same group, or other groups, was also evaluated. Data analysis showed that in ANP-based AIDS prevention and control, educating and p...
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Papers by Mia Gonzales