High relapse rate is one of the most prominent problems in addiction treatment. Alcohol Resilienc... more High relapse rate is one of the most prominent problems in addiction treatment. Alcohol Resilience Treatment (ART), an alcohol addiction therapy, is based on Cue Exposure Treatment, which has shown promising results in preliminary studies. ART aims at optimizing the core area of relapse prevention, and intends to improve patients' capability to withstand craving of alcohol. This method emphasizes the interplay of resilience and resourcefulness. It contains 6 sessions with different topics according to the stage of treatment circuit, and each session consists of 6 steps. Due to the purity and structure of the treatment rationale, it is realistic, reasonable and manageable to transform the method into a smartphone application. An ART app in Android system and an accessory of bilateral tactile stimulation were developed and will be used in a study with behavioral self-control training. This paper presents the design and realization of the smartphone based ART application. The design of a pilot study, which is to examine the benefits of a smartphone application providing behavioral self-control training, is also reported in this paper.
Disability and Rehabilitation: Assistive Technology, May 15, 2012
To explore the difference between fatigued patients with multiple sclerosis (MS) and matched heal... more To explore the difference between fatigued patients with multiple sclerosis (MS) and matched healthy controls by applying a newly developed physiological and functional data recording system. A portable wireless measurement system, named FAtigue MOnitoring System (FAMOS), has been developed, which can continuously measure electrocardiogram (ECG), body skin temperature, electromyogram, and motion parameters. In a pilot study, 17 fatigued MS patients (fatigue severity scale (FSS) = 53.9 SD 5.4) and 9 healthy matched controls (FSS = 27.2 SD 6.8) were recruited and monitored by FAMOS during the execution of functional (36 m walk test, 5- and 50-repetition sit-to-stand test) and cognitive (short-term memory tests) tests. Furthermore, oxygen saturation (SPO(2)) was measured during the functional and cognitive tests and during rest periods between these tests. Recordings from FAMOS indicate that fatigued MS patients have reduced standard deviation (SD) of the heart rate (HR) during the short-term memory test, reduced high frequency (HF) component power spectrum (representing parasympathetic activation) at rest after walk test, and higher ratio of low frequency (LF) to HF (LF/HF) during 50-repetition sit-to-stand test. FAMOS recordings can discriminate fatigued MS patients from healthy controls. The data indicate that fatigued MS patients have vagus nerve dysfunction during cognitive tests and disturbed sympathovagal balance during stressful physical tests. [Box: see text].
This paper presents our experience with developing a portable wireless medical sensor device. We ... more This paper presents our experience with developing a portable wireless medical sensor device. We use National Instruments (NI) devices and LabView for measurements studying fatigue of patients suffering multiple sclerosis (MS). Fatigue is a very frequent symptom perceived by MS patients, but the disease mechanism is poorly understood. Many efforts have been made to increase the understanding of this complex phenomenon. It has been found that fatigue might be associated with abnormalities in various anatomical brain areas. Also some secondary factors, not directly related to the disease, such as depression, sleep disorder, severe pain, use of medication and psychological factors might be of importance. However, the relationship with physiological parameters and motion activities in MS patients with fatigue across time are still unknown. Therefore, we hypothesize that we could provide a new assessment of fatigue in MS besides the questionnaires that are currently employed. Furthermore we can discover more secondary factors contributing to fatigue by measuring and monitoring a battery of physiological parameters over an extended time span (e.g. 48 hours) in MS patients without disturbing their normal life behavior. We have developed wireless medical sensor devices and conducted the following, namely Electrocardiograph, body skin temperature, eye movement detection, Electromyograph, motion detection, and muscle strength. In this paper, we describe the technology and design procedures of each measurement and present data from the first two test patients.
Reconfigurable Manufacturing Systems (RMS) have been an increasing area of interest in the resear... more Reconfigurable Manufacturing Systems (RMS) have been an increasing area of interest in the research arena. However, it seems that current literature is lacking application and implementation cases where RMS are simulated, tested, and evaluated as a feasible manufacturing concept. A Manufacturer of Consumer Goods identified the potential of the RMS concept and decided to investigate the concept in a real production installation. The result of this development is a proof of concept of a changeable and reconfigurable assembly and decoration system based on the principles of RMS. This proof of concept is meant primarily to show the physical feasibility of the system and provide a first-look into a real production application of the RMS ideas. The purpose of this paper is to present the design of the manufacturer’s RMS proof of concept, its implementation, and evaluation results.
Complex Systems Informatics and Modeling Quarterly
Shortening lifecycles and increasing complexity make product and production lifecycle processes m... more Shortening lifecycles and increasing complexity make product and production lifecycle processes more challenging than ever for manufacturing enterprises. Virtual Prototyping (VP) technologies promise a viable solution to handle such challenges in reducing time and physical builds as well as increasing quality. In previous studies, the Digital Twin (DT) based Virtual Factory (VF) concept showed significant potential to handle co-evolution by integrating 3D factory and product models with immersive and interactive 3D Virtual Reality (VR) simulation technology as well as real-time bidirectional data synchronisation between virtual and physical production systems. In this article, we present an extension to the paper “Demonstrating and Evaluating the Digital Twin Based Virtual Factory for Virtual Prototyping” presented at CARV2021. The study presents an evaluation by industry experts of the DT based VF concept for VP in the context of New Product Introduction (NPI) processes. The concep...
Digital fabrication — including additive manufacturing (AM), rapid prototyping and 3D printing — ... more Digital fabrication — including additive manufacturing (AM), rapid prototyping and 3D printing — has the potential to revolutionize the way in which products are produced and delivered to the customer. Therefore, it challenges companies to reinvent their business model — describing the logic of creating and capturing value. In this paper, we explore the implications that AM technologies have for manufacturing systems in the new business models that they enable. In particular, we consider how a consumer goods manufacturer can organize the operations of a more open business model when moving from a manufacturer-centric to a consumer-centric value logic. A major shift includes a move from centralized to decentralized supply chains, where consumer goods manufacturers can implement a “hybrid” approach with a focus on localization and accessibility or develop a fully personalized model where the consumer effectively takes over the productive activities of the manufacturer. We discuss some...
In light of the challenges of the current globalized production model, four global Danish compani... more In light of the challenges of the current globalized production model, four global Danish companies were interviewed with the purpose of exploring “glocalized production” as the new step and solution to the challenges of the “global village.” The research sought to gauge the interest on “glocalized production” by key managers of these companies, and test three hypotheses: that a definition could be established from “glocalization” aspects, that it will reduce supply chain complexity, and that it can affect organizational trust levels. The results are presented along with suggestions to pave the way for future research on this emerging topic.
High relapse rate is one of the most prominent problems in addiction treatment. Alcohol Resilienc... more High relapse rate is one of the most prominent problems in addiction treatment. Alcohol Resilience Treatment (ART), an alcohol addiction therapy, is based on Cue Exposure Treatment, which has shown promising results in preliminary studies. ART aims at optimizing the core area of relapse prevention, and intends to improve patients' capability to withstand craving of alcohol. This method emphasizes the interplay of resilience and resourcefulness. It contains 6 sessions with different topics according to the stage of treatment circuit, and each session consists of 6 steps. Due to the purity and structure of the treatment rationale, it is realistic, reasonable and manageable to transform the method into a smartphone application. An ART app in Android system and an accessory of bilateral tactile stimulation were developed and will be used in a study with behavioral self-control training. This paper presents the design and realization of the smartphone based ART application. The design of a pilot study, which is to examine the benefits of a smartphone application providing behavioral self-control training, is also reported in this paper.
Disability and Rehabilitation: Assistive Technology, May 15, 2012
To explore the difference between fatigued patients with multiple sclerosis (MS) and matched heal... more To explore the difference between fatigued patients with multiple sclerosis (MS) and matched healthy controls by applying a newly developed physiological and functional data recording system. A portable wireless measurement system, named FAtigue MOnitoring System (FAMOS), has been developed, which can continuously measure electrocardiogram (ECG), body skin temperature, electromyogram, and motion parameters. In a pilot study, 17 fatigued MS patients (fatigue severity scale (FSS) = 53.9 SD 5.4) and 9 healthy matched controls (FSS = 27.2 SD 6.8) were recruited and monitored by FAMOS during the execution of functional (36 m walk test, 5- and 50-repetition sit-to-stand test) and cognitive (short-term memory tests) tests. Furthermore, oxygen saturation (SPO(2)) was measured during the functional and cognitive tests and during rest periods between these tests. Recordings from FAMOS indicate that fatigued MS patients have reduced standard deviation (SD) of the heart rate (HR) during the short-term memory test, reduced high frequency (HF) component power spectrum (representing parasympathetic activation) at rest after walk test, and higher ratio of low frequency (LF) to HF (LF/HF) during 50-repetition sit-to-stand test. FAMOS recordings can discriminate fatigued MS patients from healthy controls. The data indicate that fatigued MS patients have vagus nerve dysfunction during cognitive tests and disturbed sympathovagal balance during stressful physical tests. [Box: see text].
This paper presents our experience with developing a portable wireless medical sensor device. We ... more This paper presents our experience with developing a portable wireless medical sensor device. We use National Instruments (NI) devices and LabView for measurements studying fatigue of patients suffering multiple sclerosis (MS). Fatigue is a very frequent symptom perceived by MS patients, but the disease mechanism is poorly understood. Many efforts have been made to increase the understanding of this complex phenomenon. It has been found that fatigue might be associated with abnormalities in various anatomical brain areas. Also some secondary factors, not directly related to the disease, such as depression, sleep disorder, severe pain, use of medication and psychological factors might be of importance. However, the relationship with physiological parameters and motion activities in MS patients with fatigue across time are still unknown. Therefore, we hypothesize that we could provide a new assessment of fatigue in MS besides the questionnaires that are currently employed. Furthermore we can discover more secondary factors contributing to fatigue by measuring and monitoring a battery of physiological parameters over an extended time span (e.g. 48 hours) in MS patients without disturbing their normal life behavior. We have developed wireless medical sensor devices and conducted the following, namely Electrocardiograph, body skin temperature, eye movement detection, Electromyograph, motion detection, and muscle strength. In this paper, we describe the technology and design procedures of each measurement and present data from the first two test patients.
Reconfigurable Manufacturing Systems (RMS) have been an increasing area of interest in the resear... more Reconfigurable Manufacturing Systems (RMS) have been an increasing area of interest in the research arena. However, it seems that current literature is lacking application and implementation cases where RMS are simulated, tested, and evaluated as a feasible manufacturing concept. A Manufacturer of Consumer Goods identified the potential of the RMS concept and decided to investigate the concept in a real production installation. The result of this development is a proof of concept of a changeable and reconfigurable assembly and decoration system based on the principles of RMS. This proof of concept is meant primarily to show the physical feasibility of the system and provide a first-look into a real production application of the RMS ideas. The purpose of this paper is to present the design of the manufacturer’s RMS proof of concept, its implementation, and evaluation results.
Complex Systems Informatics and Modeling Quarterly
Shortening lifecycles and increasing complexity make product and production lifecycle processes m... more Shortening lifecycles and increasing complexity make product and production lifecycle processes more challenging than ever for manufacturing enterprises. Virtual Prototyping (VP) technologies promise a viable solution to handle such challenges in reducing time and physical builds as well as increasing quality. In previous studies, the Digital Twin (DT) based Virtual Factory (VF) concept showed significant potential to handle co-evolution by integrating 3D factory and product models with immersive and interactive 3D Virtual Reality (VR) simulation technology as well as real-time bidirectional data synchronisation between virtual and physical production systems. In this article, we present an extension to the paper “Demonstrating and Evaluating the Digital Twin Based Virtual Factory for Virtual Prototyping” presented at CARV2021. The study presents an evaluation by industry experts of the DT based VF concept for VP in the context of New Product Introduction (NPI) processes. The concep...
Digital fabrication — including additive manufacturing (AM), rapid prototyping and 3D printing — ... more Digital fabrication — including additive manufacturing (AM), rapid prototyping and 3D printing — has the potential to revolutionize the way in which products are produced and delivered to the customer. Therefore, it challenges companies to reinvent their business model — describing the logic of creating and capturing value. In this paper, we explore the implications that AM technologies have for manufacturing systems in the new business models that they enable. In particular, we consider how a consumer goods manufacturer can organize the operations of a more open business model when moving from a manufacturer-centric to a consumer-centric value logic. A major shift includes a move from centralized to decentralized supply chains, where consumer goods manufacturers can implement a “hybrid” approach with a focus on localization and accessibility or develop a fully personalized model where the consumer effectively takes over the productive activities of the manufacturer. We discuss some...
In light of the challenges of the current globalized production model, four global Danish compani... more In light of the challenges of the current globalized production model, four global Danish companies were interviewed with the purpose of exploring “glocalized production” as the new step and solution to the challenges of the “global village.” The research sought to gauge the interest on “glocalized production” by key managers of these companies, and test three hypotheses: that a definition could be established from “glocalization” aspects, that it will reduce supply chain complexity, and that it can affect organizational trust levels. The results are presented along with suggestions to pave the way for future research on this emerging topic.
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Papers by Arne Bilberg