Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of... more Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to usual care. If bleeding continued after 30 min, or stopped and restarted within 24 h of the first dose, a second dose of 1 g of tranexamic acid or placebo could be given. Patients were assigned by selection of a numbered treatment pack from a box containing eight numbered packs that were identical apart from the pack n...
Brief about the title: The crude extract powder of Ganoderma lucidum harvested from Lafia, Nassar... more Brief about the title: The crude extract powder of Ganoderma lucidum harvested from Lafia, Nassarawa State of Nigeria during the rainy season was analyzed for proximate contents, phytochemical constituents and mineral composition using various standard methods. Description of the experiment and procedures: The harvested Ganoderma lucidum was air dried at 37 0 C and grinded to powder; this was preliminary analyzed for proximate contents, phytochemical constituents. The crude powder was subjected to soxhlet extraction at 40 0 C using Methanol, Ethylacetate and N-butanol to obtain different organic solvent fractions, these were then concentrated in vacuo at 24 0 C for 48 hours to obtain different solvent extract fractions. These extracts were then analyzed for phytochemical contents using standards methods. Results: Analysis for proximate constituent showed Moisture contents was 10.54%, Total ash 5.93%, Protein 17.55%, Crude Fats 2.60%, Crude Fiber 30.25%, Carbohydrates 33.13%, and Nit...
Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of... more Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to usual care. If bleeding continued after 30 min, or stopped and restarted within 24 h of the first dose, a second dose of 1 g of tranexamic acid or placebo could be given. Patients were assigned by selection of a numbered treatment pack from a box containing eight numbered packs that were identical apart from the pack n...
Brief about the title: The crude extract powder of Ganoderma lucidum harvested from Lafia, Nassar... more Brief about the title: The crude extract powder of Ganoderma lucidum harvested from Lafia, Nassarawa State of Nigeria during the rainy season was analyzed for proximate contents, phytochemical constituents and mineral composition using various standard methods. Description of the experiment and procedures: The harvested Ganoderma lucidum was air dried at 37 0 C and grinded to powder; this was preliminary analyzed for proximate contents, phytochemical constituents. The crude powder was subjected to soxhlet extraction at 40 0 C using Methanol, Ethylacetate and N-butanol to obtain different organic solvent fractions, these were then concentrated in vacuo at 24 0 C for 48 hours to obtain different solvent extract fractions. These extracts were then analyzed for phytochemical contents using standards methods. Results: Analysis for proximate constituent showed Moisture contents was 10.54%, Total ash 5.93%, Protein 17.55%, Crude Fats 2.60%, Crude Fiber 30.25%, Carbohydrates 33.13%, and Nit...
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