Kosheeka

Explore the intricacies of the drug discovery process with Kosheeka. The removal of mandatory animal testing is a significant aspect of the FDA Modernization Act 2.0. The utilization of human primary cells for preclinical and toxicity testing allows for the acquisition of more pertinent data regarding human biology. Ask for a quotation from Kosheeka at +919654321400. #drugdiscovery #kosheeka #primarycells #biotech #fda #biology

Acute liver failure (ALF) is a critical life-threatening disease that occurs due to a rapid loss in hepatocyte functions. Hepatocyte transplantation holds great potential for ALF treatment, as it rapidly supports liver biofunctions and enhances liver regeneration. However, hepatocyte transplantation is still limited by renewable and ongoing cell sources. In addition, intravenously injected hepatocytes are primarily trapped in the lungs and have limited efficacy because of the rapid clearance in vivo. In present study, a Y-shaped DNA nanostructure is designed to deliver microRNA-122 (Y-miR122), which could induce the hepatic differentiation and maturation of human mesenchymal stem cells. mRNA sequencing analysis revealed that the Y-miR122 promoted important hepatic biofunctions of the induced hepatocyte-like cells including fat and lipid metabolism, drug metabolism, and liver development. Read More: https://lnkd.in/g_MY8K2Q #mesenchymalstemcells #stemcells #kosheeka #biotech #hepatocytes

Days to wait for your research products are all over! With Kosheeka ready-to-use cell culture products engage in uninterrupted research. Get quotation for various origin primary cells that align with your needs at 096543 21400 #primarycells #cellculture #cellbiology #research #kosheeka

Get ready to use primary cells for your experiments in a fortnight! Contact Kosheeka at +919654321400 to get a quote for the same. #primarycells #biomaterials #cellculture #biotechnology #kosheeka

Looking for high-quality Peripheral Blood Mononuclear Cells sourced and prepared by Kosheeka for your advanced research needs! Discover the foundation of groundbreaking studies with our PBMCs. #research #cellculture #cellbiology #kosheeka #biotechnology

Number of cells is crucial in each and every experiment. We at Kosheeka understand this and for this reason, we bring forth primary cells that have more than 90% viability in every vial. We have several quality parameters in place to ensure that you get sufficient cells for your experiments. #primarycells #cellculture #bioinformatics #kosheeka #biotechnology #lifesciences #research

International Society for #CellTherapy (ISCT) established the characteristics of #MSCs to be used for research and therapeutics. Among the criteria, one essential factor is the surface markers that distinguish these cells from other. These cells must express CD73, CD 90 and CD105 to be recognized as the true #stemcells. Get the cells that have these surface markers for your #research with #Kosheeka. Call us at +919654321400 to know more about MSCs.

Cardiovascular diseases are the most common cause of death globally. Accurately modeling cardiac homeostasis, dysfunction, and drug response lies at the heart of cardiac research. Adult human primary cardiomyocytes (hPCMs) are a promising cellular model, but unstable isolation efficiency and quality, rapid cell death in culture, and unknown response to cryopreservation prevent them from becoming a reliable and flexible in vitro cardiac model. Combing the use of a reversible inhibitor of myosin II ATPase, (-)-blebbistatin (Bleb), and multiple optimization steps of the isolation procedure, we achieved a 2.74-fold increase in cell viability over traditional methods, accompanied by better cellular morphology, minimally perturbed gene expression, intact electrophysiology, and normal neurohormonal signaling. Further optimization of culture conditions established a method that was capable of maintaining optimal cell viability, morphology, and mitochondrial respiration for at least 7 days. Read More: https://lnkd.in/gqA4Thvm

Get animal cell culture products that meet the highest quality of industrial standards. Kosheeka's biomaterial is manufactured in labs that are compliant to ISO 9001 & 13485 standards. Give you research the products that are trusted by leaders in the field. #animalcellculture #cellculture #biomaterials #kosheeka #primarycells

Cells and tissues rely on red blood cells (RBCs) circulation for oxygen supply. Analyzing tissue metabolism during normal and pathological activity requires quantifying hemodynamics and blood oxygenation at high resolution in situ. Two-photon (2P) microscopy is a reference technique for measuring RBC microcirculation and blood oxygenation using exogenous phosphorescent probes and is increasingly used to study brain oxygenation and physiology. Read More: https://lnkd.in/gHUCqbCw #redbloodcells #RBC #tissueengineering #cellculture #Biotech #kosheeka