Apr 9, 2018 · Our data suggest that Vms1 can potentially hydrolyse peptidyl-tRNA chains on this leading stalled ribosome without prior splitting by Dom34–Hbs1–Rli1.
Nov 9, 2018 · Here we show that the Cdc48 adaptor Vms1 is a peptidyl-tRNA hydrolase. Similar to classical eRF1, Vms1 activity is dependent on a conserved catalytic glutamine.
Hbs1–Dom34 and the ATPase Rli1 dissociate stalled ribosomes into 40S and 60S subunits. However, the 60S subunits retain the peptidyl-tRNA nascent chains, which ...
Hbs1–Dom34 and the ATPase Rli1 dissociate stalled ribosomes into 40S and 60S subunits. However, the 60S subunits retain the peptidyl-tRNA nascent chains, which ...
ANKZF1 liberates peptidyl-tRNAs from stalled ribosomes such that the tRNA is checked in an obligate way for integrity before reentry into the translation ...
Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes ... Authors: Rati Verma; Kurt M. Reichermeier; A. Maxwell Burroughs; Robert ...
Oct 18, 2018 · Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes. Nature, 557 (2018), pp. 446-451. Crossref View in ...
... (Vms1-Like Release Factor-1) clade . They have been identified as peptidyl-tRNA hydrolases that release nascent chains from stalled ribosomes . ANKZF1, VMS1 ...
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Jun 1, 2021 · Pubmed ID, Year, Title, Citations. 29632312, 2018, Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes.
Working model of Vms1 function at stalled ribosomes In non-stop decay... Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes.