This analysis shows that network features are useful for predicting physical binding and that the topological structure of the functional network also contains ...
Aug 15, 2012 · We present a systematic assessment of seven different network features extracted from the topology of functional genetic networks.
Results: Herein, we present a systematic assessment of seven different network features extracted from the topology of functional genetic networks and we ...
It has been recognized that the topology of molecular networks provides information about the certainty and nature of individual interactions.
The analysis shows that network features are at least as predictive for the tasks the authors tested as non-network features, however, feature importance ...
Motivation: It has been recognized that the topology of molecular networks provides information about the certainty and nature of individual interactions.
We found a strong relationship between evolved physical–chemical properties of protein interactions and their abundances due to a “frustration” effect.
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Protein-protein interaction plays key role in predicting the protein function of target protein and drug ability of molecules.
We find that, as in the case of protein folding, the native topology is the major factor that governs the choice of binding mechanism.
Feb 14, 2020 · A topology-based network tree is constructed by integrating the topological representation and NetTree for predicting protein–protein interaction ΔΔG.