The DT40 web site: sampling and connecting the genes of a B cell line
pmc.ncbi.nlm.nih.gov › PMC99062
Here, we present the DT40 web site (http://genetics.hpi.uni-hamburg.de/dt40.html), which includes a comprehensive database of chicken bursal ESTs to identify ...
Oct 24, 2024 · Here, we present the DT40 web site (http://genetics.hpi.uni-hamburg.de/dt40.html), which includes a comprehensive database of chicken bursal ...
The chicken DT40 cell line is derived from a bursal B cell lymphoma and undergoes ongoing V gene conversion in culture.
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DT40 is a stable cell line, established after infection of chicken bursal lymphoblasts with an avian leukosis virus ( 11 ). Its exceptional feature is the high ...
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The DT40 cell line is a versatile system, that allows the study of specific signal transduction pathways such as those activated by the BCR or induced by ...
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Using the chicken B cell line DT40 as a model, we use SPPLAT to provide the first proteomic analysis of any BCR cluster using proximity labeling. We detect ...
May 26, 2020 · DT40 is a chicken-derived B cell line in which GC continuously occurs at the immunoglobulin loci. We discovered that this GC frequency is ...
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The reported phenotype provides the first genetic evidence of a link between double-strand break repair and homologous recombination in vertebrate cells.
DT40 are lymphoblasts that were isolated from the bursa of a patient with lymphoma. It has applications in immunology.
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We mapped coding sequence mutations that are unique to the DT40 genome; mutations inactivating the PIK3R1 and ATRX genes likely contributed to the oncogenic ...