Predicting the kinetics of reactions involving nucleic acid strands is a fundamental task in biology and biotechnology. Reaction kinetics can be modeled as an elementary step continuous-time Markov chain, where states correspond to secondary structures and transitions correspond to base pair formation and breakage.
Feb 25, 2023 · We propose a new method, called pathway elaboration, to handle these scenarios. Pathway elaboration builds a truncated continuous-time Markov ...
We tackle the problem of predicting the kinetics of nucleic acid reactions. We propose pathway elaboration, a truncated continuous-time Markov chain approach.
We propose a new method, called pathway elaboration, to handle these scenarios. Pathway elaboration builds a truncated continuous-time Markov chain through both ...
Co-authors ; Predicting DNA kinetics with a truncated continuous-time Markov chain method. S Zolaktaf, F Dannenberg, M Schmidt, A Condon, E Winfree.
This software implements the pathway elaboration method for (multiple) interacting nucleic acid strands using the Multistrand simulator [2].
Predicting DNA kinetics with a truncated continuous-time Markov chain method. S Zolaktaf, F Dannenberg, M Schmidt, A Condon, E Winfree. Computational Biology ...
For predicting the kinetics of nucleic acid reactions, continuous-time. Markov chains (CTMCs) are widely used. The rate of a reaction can be ob-.
Imprecise Continuous-Time Markov Chains: Efficient Computational Methods ... Predicting DNA kinetics with a truncated continuous-time Markov chain method.
Many simulators model the kinetics of interacting nucleic acid strands as continuous-time Markov chains (CTMCs). States of the CTMCs represent a collection of ...