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In this paper we present an investigation of Cancer Genome Atlas data that correlates morphology with recently discovered molecular subtypes of glioblastoma.
Our top-down analysis demonstrates the power of morphological signatures to predict clinically-relevant molecular tumor subtypes, with 85.4% recognition of the ...
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Aug 4, 2023 · This study aimed at specific characterization of glioblastoma progression in male tolerant and susceptible to hypoxia Wistar rats.
May 17, 2024 · High-neural glioblastomas exhibit hypomethylated CpG sites and upregulation of genes associated with synaptic integration. Single-cell ...
Jan 24, 2012 · Morphologic signatures that represent patient-specific tumor morphology are derived from the analysis of hundreds of millions of cells in ...
Jan 19, 2010 · Here, we show that genomic profiling defined four subtypes of tumors with a common morphologic diagnosis of GBM. The reproducibility of this ...
Methodology was applied to 162 glioblastomas from The Cancer Genome Atlas to identify morphology-driven clusters and their clinical and molecular correlates.
We investigated whether specific nuclear features were correlated with the oligodendrocyte signature genes HOXD1, MBP, and PLP1, which were highly correlated ...
Nov 12, 2021 · We derived three distinct radiomic MRI subtypes for glioblastoma that highly correlate with the patients' survival and molecular genetic characteristics.
Aug 28, 2024 · In culture, these cells form spatial structures that share morphological aspects with their source tumors. We collected 17,000 phase contrast ...