scholar.google.com › citations
Another challenge in predicting protein function is that predictions based on sequence or structural homology can be inaccurate because even proteins with significant amino acid sequence identity can have different functions.
This review focuses on the various approaches that have been developed to predict function from the scale of the atom to that of the organism. Similarities in ...
People also ask
What are the challenges in protein structure prediction?
What is a disadvantage of protein sequencing?
Why is it hard to predict protein structure?
What is the protein sequence design problem?
Homology, the evolutionary descent of genes from a common ancestor,1 often provides vital evidence in the prediction of molecular function. That two genes are.
Oct 19, 2023 · CAS interviews Iddo Friedberg, Ph.D., about protein prediction models, their capabilities, and the bottlenecks that must be addressed.
Missing: Issues | Show results with:Issues
Jul 1, 2024 · Sequence-based methods focus on the protein sequence to predict protein function by extracting potential features related to function from it.
Issues in predicting protein function from sequence. Abstract: Identifying homologues, defined as genes that arose from a common evolutionary ancestor, is ...
Feb 14, 2024 · We have developed DeepGO-SE, a method that predicts GO functions from protein sequences using a pretrained large language model.
The problem with structural genomics targets is that many of them do not have any close sequence similarity to proteins of known function. In recent years, ...
Jul 3, 2023 · Other complications in understanding protein functions are due to many proteins having more than one function or very small differences in ...
Mar 20, 2007 · Feature selection and the class imbalance problem in predicting protein function from sequence. Appl Bioinformatics. 2005, 4 (3): 195-203 ...