By means of conserved TF cluster analysis, two different TF modules have been identified in the promoter and first intron of FGFR3 gene. These modules contain ...
Integrative Analysis of the Regulatory Region of the FGFR3 Oncogene
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Abstract. The study of transcriptional regulation often needs the integration of di- verse yet independent data. In the present work, sequence conservation, ...
Integrative Analysis of the Regulatory Region of the FGFR3 Oncogene. https://doi.org/10.1007/978-3-642-19914-1_27 · Full text.
Josep Bau , Marta Cullell, Jordi Solé-Casals : Integrative Analysis of the Regulatory Region of the FGFR3 Oncogene. PACBB 2011: 201-204.
In the present work, sequence conservation, predic-tion of transcription factor binding sites (TFBS) and gene expression analysis have been applied to the ...
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Oncogenic alterations in the cell cycle regulatory genes ... Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal.
The FGFR3-TACC3 fusion is an oncogenic driver in diverse malignancies, including bladder cancer, characterized by upregulated tyrosine kinase activity.
Apr 16, 2021 · We demonstrated that the genomic and transcriptomic subtypes showed independent prognostic value when compared to clinical risk factors.
The fibroblast growth factor receptor 3 (FGFR3) gene has long been associated with bladder cancer oncogenesis and recently become a therapeutic target (12). It ...
Genomic aberrations in the FGFR pathway - Annals of Oncology
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Nov 20, 2013 · The fibroblast growth factor receptor (FGFR) cascade plays crucial roles in tumor cell proliferation, angiogenesis, migration and survival.