Interleukin-1β is a drug target in rheumatoid arthritis and several auto-immune disorders. In this study, a set of 48 compounds with the determined IC50 values ...
Docking results showed 7 compounds as potential IL-1β inhibitors. Abstract. Interleukin-1β is a drug target in rheumatoid arthritis and several auto-immune ...
Oct 22, 2024 · Interleukin-1β is a drug target in rheumatoid arthritis and several auto-immune disorders. In this study, a set of 48 compounds with the ...
Jun 21, 2023 · Primarily, the docking-based screening was performed by selecting the crucial residues of IL-1β interface to retrieve the potential compounds.
Oct 1, 2015 · This study provides valuable insight for designing more potent and selective inhibitors for the treatment of inflammatory diseases.
In silico identification of novel IL-1β inhibitors to target protein-protein interfaces · S. Halim, Muhammad Jawad, +3 authors. T. Husnain · Published in Comput.
Jun 21, 2023 · A docking-based strategy was used to screen the TCM (Traditional Chinese Medicine) database to identify possible IL-1β inhibitors with desirable ...
Missing: novel target
Dec 9, 2024 · Primarily, the docking-based screening was performed by selecting the crucial residues of IL-1β interface to retrieve the potential compounds.
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In silico identification of novel IL-1β inhibitors to target protein-protein interfaces. Display Omitted The study encompasses QSAR modeling, pharmacophore ...
May 6, 2022 · The objective of this study was to engineer a low-molecular-weight version of IL-1RA with increased affinity and enhanced antagonistic activity for potential ...