Decomposition of Gene Expression State Space Trajectories. Jessica C. Mar, John Quackenbush. Jessica C. Mar. Affiliation: Department of Biostatistics, Harvard ...
Dec 24, 2009 · To this end, we extend the work of Huang et al. [3] by decomposing the state space trajectories into components comprising two sets of genes, a ...
The expression mosaics for the ATRA and DMSO-stimulated time course data capture spatial patterns in the data as the system iterates through the time series.
Decomposition of Gene Expression State Space Trajectories ... ATRA is able to diffuse freely across the cell membrane. A pair of cellular retinoic acid binding ...
DMSO upregulates the tumor suppressor protein PTEN in HL-60 cells. This increase in PTEN expression and activity is brought about by the activation of NF-κB ...
The application of gene expression state space trajectories to capture cell fate transitions at the genome-wide level is one approach currently used in the ...
Oct 2, 2024 · The spectral decomposition of the HL can be used to decompose flows and trajectories, on the edges into gradient, curl, and harmonic components ...
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Robust decomposition of cell type mixtures in spatial transcriptomics. Nat. Biotechnol.40, 1–10 (2021). [DOI] [PMC free article] [PubMed]; 76. Stuart T, et ...
Decomposition of Gene Expression State Space Trajectories. Overview of attention for article published in PLoS Computational Biology, December 2009. Altmetric ...
Jun 8, 2024 · D. With this decomposition algorithm, we effectively divide the problem of solving CMEs into several lower-scale computational sub-problems, and ...