PathAct implements an advanced graphical interface that provides a unique interactive working environment in which the suitability of potentially actionable genes, that could eventually become drug targets for personalized or individualized therapies, can be easily tested.
May 2, 2016
Jul 8, 2016 · The discovery of actionable targets is crucial for targeted therapies and is also a constituent part of the drug discovery process.
May 2, 2016 · The discovery of actionable targets is crucial for targeted therapies and is also a constituent part of the drug discovery process.
PathAct implements an advanced graphical interface that provides a unique interactive working environment in which the suitability of potentially actionable ...
Actionable pathways: interactive discovery of therapeutic targets using signaling pathway models ... Authors: Francisco Salavert; Marta R. Hidago; Alicia Amadoz ...
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Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients · Using activation status of ...
Jun 20, 2018 · Our study demonstrates that high throughput signaling pathway analysis will significantly aid in identifying actionable alterations in rare tumors.
Missing: interactive | Show results with:interactive
Mechanistic models offer an opportunity to reconsider alternative targets on the pathways relevant for the therapeutic interventions that lead to similar ...
Mar 1, 2019 · We present Metabolizer, a web-based application that offers an intuitive, easy-to-use interactive interface to analyze differences in pathway metabolic module ...
Here, we use mechanistic modeling of signaling circuits, which reveals a complex functional landscape at single-cell level.