Cytidine triphosphate
Appearance
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Names | |
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IUPAC name
Cytidine 5′-(tetrahydrogen triphosphate)
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Systematic IUPAC name
O1-{[(2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate | |
Other names
CTP; Cytidine-5'-triphosphate
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.000.556 |
MeSH | Cytidine+triphosphate |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C9H16N3O14P3 | |
Molar mass | 483.156 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Cytidine triphosphate (CTP) is a pyrimidine nucleoside triphosphate. CTP, much like ATP, consists of a ribose sugar, and three phosphate groups. The major difference between the two molecules is the base used, which in CTP is cytosine.
CTP is a substrate in the synthesis of RNA.
CTP is a high-energy molecule similar to ATP, but its role as an energy coupler is limited to a much smaller subset of metabolic reactions. CTP is a coenzyme in metabolic reactions like the synthesis of glycerophospholipids, where it is used for activation and transfer of diacylglycerol and lipid head groups,[1] and glycosylation of proteins.
CTP acts as an inhibitor of the enzyme aspartate carbamoyltransferase, which is used in pyrimidine biosynthesis.[2]
See also
[edit]References
[edit]- ^ Buchanan BB, Gruissem W, Jones RL (2000). Biochemistry & molecular biology of plants (1st ed.). American society of plant physiology. ISBN 978-0-943088-39-6.
- ^ Blackburn, G. Michael. Nucleic Acids in Chemistry and Biology. The Royal Society of Chemistry, 2006, p. 119-120.