Search results

(DKK4). Both a cysteine to tyrosine substitution at residue 63 (C63Y) and an alanine to valine substitution at residue 18 (A18V) result in decreased DKK4...

point substitution mutation results in a change in a single nucleotide and can be either synonymous or nonsynonymous. A synonymous substitution replaces...

Display Result in Text Editor. Substitution Models in MEGA allow various options with different attributes of substitution models for both DNA and protein...

A protein's primary structure refers to its amino acid sequence. A substitution of one amino acid for another can impair protein function and tertiary...

proteins). Substitution models are used to calculate the likelihood of phylogenetic trees using multiple sequence alignment data. Thus, substitution models...

nucleotide substitution. Typical amino acids - there are several other amino acids which they can change into through single nucleotide substitution. Typical...

genetics, where an experiment (e.g. a drug, cross, or gene transfer) resulting in such a restoration is said to rescue the normal phenotype. residue An...

transition at cDNA position 341. This leads to an alanine to valine residue substitution at amino acid position 114, a location highly conserved in all organisms...

sequence (or canonical sequence) is the calculated sequence of most frequent residues, either nucleotide or amino acid, found at each position in a sequence...

In genetics and bioinformatics, a single-nucleotide polymorphism (SNP /snɪp/; plural SNPs /snɪps/) is a germline substitution of a single nucleotide at...

underlie its pigmentation. The resultant single amino acid substitution introduces an alanine residue that protrudes into the transport protein's central passageway...

enzyme that removes phosphate groups that have been attached to amino acid residues of proteins Protein purification, series of processes intended to isolate...

express recombinant proteins whose canonical Trp and Met residues are completely substituted with different medium-supplemented related analogs. This...

deficiency resulting from a C-to-T substitution in exon 5 of the ornithine transcarbamylase gene". American Journal of Human Genetics. 45 (1): 123–7. PMC 1683378...

literature, of which 41 are thought to result in amino acid substitutions or deletions at critical residues. Ser113Leu (338C>T) is the most common mild mutation...

In bioinformatics, the BLOSUM (BLOcks SUbstitution Matrix) matrix is a substitution matrix used for sequence alignment of proteins. BLOSUM matrices are...

was an amino acid substitution from a Glycine to Aspartic acid, and the mutation of F. kawamurai was also an amino acid substitution from Glycine to Arginine...

fucosylation and sialylation reactions. Additionally, substitution with more GlcNAc residues can yield tri- and tetra-antennary molecules. Not all structures...

receptor. The mutation causes substitution of codon 206 from arginine to histidine in the ACVR1 protein. This substitution causes abnormal activation of...

determined that Glu540 is the nucleophilic residue. Though the particular type of nucleophilic substitution employed by β-glucuronidase is unclear, evidence...