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  • Thumbnail for Mevalonate kinase deficiency
    (MKD) is an autosomal recessive metabolic disorder that disrupts the biosynthesis of cholesterol and isoprenoids. It is a rare genetic disorder, but a...
    17 KB (1,960 words) - 22:12, 13 November 2024
  • Thumbnail for Penicillin
    usually tolerate cephalosporins (another group of β-lactam) because the immunoglobulin E (IgE) cross-reactivity is only 3%. Penicillin was discovered in 1928...
    99 KB (10,660 words) - 22:16, 23 December 2024
  • Thumbnail for J chain
    Tartakoff A, Vassalli P (November 1979). "Plasma cell immunoglobulin M molecules. Their biosynthesis, assembly, and intracellular transport". The Journal...
    20 KB (2,375 words) - 10:22, 3 December 2023
  • Thumbnail for Lipopolysaccharide
    T, Carroll MC, Chen J (December 1998). "A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection". The Journal...
    63 KB (7,186 words) - 05:14, 9 January 2025
  • Thumbnail for Pyocyanin
    redox-active properties, pyocyanin generates reactive oxygen species. Pyocyanin biosynthesis begins with the synthesis of the phenazine-1-carboxylic acid (PCA) core...
    17 KB (1,971 words) - 18:28, 5 February 2024
  • Thumbnail for Sulfamethoxazole
    Gel-Coombs spectrum of hyperactivity reactions. Type 1 reactions include immunoglobulin E (IgE)-mediated reactions such as urticaria, angioedema, and anaphylaxis...
    12 KB (997 words) - 20:14, 5 December 2024
  • Thumbnail for Fusion gene
    in lymphomas, where oncogenes are juxtaposed to the promoters of the immunoglobulin genes. Oncogenic fusion transcripts may also be caused by trans-splicing...
    17 KB (1,928 words) - 19:40, 5 August 2024
  • Thumbnail for N-linked glycosylation
    this linkage comes from the hydrolysis of a pyrophosphate molecule. The biosynthesis of N-linked glycans occurs via three major steps: Synthesis of dolichol-linked...
    25 KB (2,522 words) - 19:10, 11 December 2024
  • Thumbnail for Cortisol
    It is paradoxical that cortisol promotes not only gluconeogenesis (biosynthesis of glucose molecules) in the liver, but also glycogenesis (polymerization...
    78 KB (8,617 words) - 00:09, 17 December 2024
  • reaction due to the immune system of a hypothetical receiver producing immunoglobulins against that antigen—in the case of a Bombay patient, not only against...
    10 KB (1,374 words) - 19:18, 18 December 2024
  • Thumbnail for Binding immunoglobulin protein
    Binding immunoglobulin protein (BiPS) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a protein that...
    31 KB (3,521 words) - 20:22, 5 December 2024
  • majority of people seem to possess IgM, IgG or both of these types of immunoglobulins capable of binding this glycan. An interesting particularity of rhamnose...
    6 KB (523 words) - 16:17, 6 June 2024
  • Understanding them is important in organ transplants. Hinge regions of immunoglobulins contain highly O-glycosylated regions between individual domains to...
    28 KB (3,180 words) - 05:01, 11 November 2024
  • Thumbnail for IGHMBP2
    DNA-binding protein SMUBP-2, also known as immunoglobulin helicase μ-binding protein 2 (IGHMBP2) and cardiac transcription factor 1 (CATF1) – is a protein...
    4 KB (523 words) - 00:30, 4 March 2023
  • Thumbnail for Transglutaminase
    reactions. These TGases have a three or four-domain organization, with immunoglobulin-like domains surrounding the central catalytic domain. The core domain...
    17 KB (1,504 words) - 16:27, 22 September 2024
  • Thumbnail for Scleroderma
    azathioprine, methotrexate, cyclophosphamide, mycophenolate, intravenous immunoglobulin, rituximab, sirolimus, alefacept, and the tyrosine kinase inhibitors...
    38 KB (3,337 words) - 22:36, 4 January 2025
  • Thumbnail for Index of biochemistry articles
    protein - eye proteins fab immunoglobulin - facilitated diffusion - factor VIII - FADH - FADH2 - Fat - Fatty acid - fc immunoglobulin - fc receptor - feedback...
    29 KB (2,471 words) - 04:50, 19 January 2024
  • Thumbnail for Chlamydia trachomatis
    products are, in turn, brought into the PPP to create nucleotides and for biosynthesis. This type of growth is very similar to the Warburg effect observed in...
    47 KB (5,493 words) - 19:18, 3 January 2025
  • Thumbnail for Mycophenolic acid
    immune-mediated disorders including Behçet's disease, pemphigus vulgaris, immunoglobulin A nephropathy, small vessel vasculitides, and psoriasis. It is also...
    40 KB (3,565 words) - 03:57, 10 December 2024
  • described as a mitochondrial porphyrin transporter essential for heme biosynthesis, but it is also suspected to contribute to anticancer drug resistance...
    21 KB (1,388 words) - 20:28, 8 November 2024
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