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present as either a free monomer called G-actin (globular) or as part of a linear polymer microfilament called F-actin (filamentous), both of which are essential...

dependent on actin polymerization. Many of the physiologic effects that cells experience after exposure to TcdA can be linked to disregulation of actin polymerization...

in particular the actin network. Intracellular microbes, such as the bacteria Salmonella and Shigella, elicit actin polymerization in host cells that...

effects on the cytoskeleton: for example, Latrunculin both prevents actin polymerization as well as enhancing its rate of depolymerization. Typically the...

of actin. There are several toxins that have been known to limit the polymerization of actin. Cytochalasin is a toxin that will bind to the actin polymer...

actin polymerization. The first step in actin polymerization, after polymerization is initiated, is the deprotonation of the thiol group of G-actin....

products and toxins produced by certain sponges, including genus Latrunculia and Negombata, whence the name is derived. It binds actin monomers near...

part. C2-like toxins: the "A" parts are G-actin ADP-ribosyltransferases, which carry out a modification that prevents actin from polymerizing. Members include...

example, to the lysis of vacuolar membranes or reorganization of actin polymerization to facilitate intracellular motility of Shigella bacteria inside...

move within eukaryotic cells by explosive polymerization of actin filaments (known as comet tails or actin rockets). Once Listeria monocytogenes enters...

Actin-binding proteins (also known as ABPs) are proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both. Many actin-binding...

F-actin polymerization in postsynaptic dendritic spines at excitatory synapses. Recent research has been done to target this F-actin polymerization by...

surface invaginations and sometimes involves the recruitment of actin-polymerization machinery that further aid in the pinching off of the vesicle wall...

ability to bind to actin filaments and block polymerization and the elongation of actin. As a result of the inhibition of actin polymerization, cytochalasins...

machinery to move around inside the host cell. It induces directed polymerization of actin by the ActA transmembrane protein, thus pushing the bacterial cell...

glutamate and the ε-amino group of lysine in actin. This process stops actin polymerization in the host cell. For isopeptide bonds linking one protein to another...

found to react stoichiometrically with actin, strongly promote actin polymerization, and stabilize actin polymers. Phalloidin functions differently at various...

Rho GTPases have been found. Two molecules that directly stimulate actin polymerization are the Arp2/3 proteins and the Diaphanous-related formins. Rho/Rac...

Actin, cytoplasmic 2, or gamma-actin is a protein that in humans is encoded by the ACTG1 gene. Gamma-actin is widely expressed in cellular cytoskeletons...

trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. ARF6 can...