DALT: Difference between revisions

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+{{short description|Chemical compound}}
 {{Drugbox
+| Watchedfields = changed
-| verifiedrevid = 450480466
+| verifiedrevid = 451559106
-| IUPAC_name = ''N''-allyl-''N''-[2-(1''H''-indol-3-yl)ethyl]prop-2-en-1-amine
+| IUPAC_name = ''N''-Allyl-''N''-[2-(1''H''-indol-3-yl)ethyl]prop-2-en-1-amine
 | image = DALT-structure.png
@@ Line 7: / Line 9: @@
 | tradename =
 | pregnancy_category =
+| legal_DE = NpSG
-| legal_status = Uncontrolled <small>(but may be covered under the [[Federal Analogue Act]] in the [[United States]] and under similar bills in other countries)</small>
+| legal_UK = Class A
-| routes_of_administration = [[Mouth|Oral]], [[Insufflated]], [[Rectal]], [[Smoked]], [[Intramuscular|IM]], [[Intravenous|IV]]
+| legal_US = Analogue
+| legal_US_comment = (possibly)
+| legal_status = May be covered under similar Analogue bills in other countries
+| routes_of_administration = {{citation needed span|text=[[Mouth|Oral]], [[Insufflation (medicine)|insufflated]], [[Rectal (medicine)|rectal]], [[smoking|smoked]], [[Intramuscular injection|IM]], [[Intravenous therapy|IV]]|date=October 2014}}
 <!--Pharmacokinetic data-->
@@ Line 14: / Line 20: @@
 | metabolism =
 | elimination_half-life =
 | excretion =
 <!--Identifiers-->
-| CAS_number =
+| CAS_number = 60676-77-9
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = 85113MO9BC
 | ATC_prefix = none
 | ATC_suffix =
@@ Line 26: / Line 34: @@
 <!--Chemical data-->
 | C=16 | H=20 | N=2
+| smiles = C=CCN(CC=C)CCc2c[nH]c1ccccc12
-| molecular_weight = 240.34 g/mol
-| smiles = C=CCN(CC=C)CCc2cnc1ccccc12
-| InChI = 1/C16H20N2/c1-3-10-18(11-4-2)12-9-14-13-17-16-8-6-5-7-15(14)16/h3-8,13,17H,1-2,9-12H2
-| InChIKey = LQEATNFJCMVKAC-UHFFFAOYAB
 | StdInChI_Ref = {{stdinchicite|correct|chemspider}}
 | StdInChI = 1S/C16H20N2/c1-3-10-18(11-4-2)12-9-14-13-17-16-8-6-5-7-15(14)16/h3-8,13,17H,1-2,9-12H2
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 }}
+'''''N'',''N''-Diallyltryptamine''' ('''DALT''') is a [[tryptamine]] [[derivative (chemistry)|derivative]] which has been identified as a new psychoactive substance.<ref name="pmid26297461">{{cite journal | vauthors = Michely JA, Helfer AG, Brandt SD, Meyer MR, Maurer HH | title = Metabolism of the new psychoactive substances N,N-diallyltryptamine (DALT) and 5-methoxy-DALT and their detectability in urine by GC-MS, LC-MSn, and LC-HR-MS-MS | journal = Analytical and Bioanalytical Chemistry | volume = 407 | issue = 25 | pages = 7831–42 | date = October 2015 | pmid = 26297461 | doi = 10.1007/s00216-015-8955-0 | s2cid = 26086597 | url = http://researchonline.ljmu.ac.uk/id/eprint/3406/1/ABC-01148-2015.R1.pdf }}</ref><ref name="pmid27933361">{{cite journal | vauthors = Michely JA, Brandt SD, Meyer MR, Maurer HH | title = n, and LC-HR-MS/MS | journal = Analytical and Bioanalytical Chemistry | volume = 409 | issue = 6 | pages = 1681–1695 | date = February 2017 | pmid = 27933361 | doi = 10.1007/s00216-016-0117-5 | s2cid = 206920201 | url = http://researchonline.ljmu.ac.uk/id/eprint/4885/1/ABC_5F_7Me_5%2C6MD-DALT_accepted.pdf }}</ref>  It has been used as an intermediate in the preparation of [[radiolabeled]] [[diethyltryptamine]].<ref>{{cite journal | vauthors = Brandt SD, Tirunarayanapuram SS, Freeman S, Dempster N, Barker SA, Daley PF, Cozzi NV, Martins CP | display-authors = 6 | title = Microwave-accelerated synthesis of psychoactive deuterated N,N-dialkylated-[α,α,β,β-d4]-tryptamines | journal = Journal of Labelled Compounds and Radiopharmaceuticals | date = 2008 | volume = 51 | issue = 14 | pages = 423–429 | doi = 10.1002/jlcr.1557}}</ref>
-'''''N'',''N''-Diallyltryptamine''' ('''DALT''') is a [[psychedelic drug|psychedelic]] [[drug]] of the [[tryptamine]] class.<ref name="urlThe Psychedelic Index - DALT (ahead of print)">{{cite web | url = http://www.bluelight.ru/vb/showpost.php?p=2104770&postcount=15 | title = The Psychedelic Index - DALT (ahead of print) | author = Alexander Shulgin | coauthor = Ann Shulgin | accessdate = April 2010}}</ref> [[Alexander Shulgin]] reports that DALT is active at 42 mg [[mouth|orally]], producing a +1 on the [[Shulgin scale]], and being back to baseline by 4 hours.<ref name="urlThe Psychedelic Index - DALT (ahead of print)">{{cite web | url = http://www.bluelight.ru/vb/showpost.php?p=2104770&postcount=15 | title = The Psychedelic Index - DALT (ahead of print) | author = Alexander Shulgin | coauthor = Ann Shulgin | accessdate = April 2010}}</ref> It is said to have a similar [[potency (pharmacology)|potency]] to [[N,N-dimethyltryptamine|DMT]], being [[activity (chemistry)|active]] at doses of approximately 40-100 mg, and to have a duration of about 2-4 hours.<ref name="urlThe Psychedelic Index - DALT (ahead of print)">{{cite web | url = http://www.bluelight.ru/vb/showpost.php?p=2104770&postcount=15 | title = The Psychedelic Index - DALT (ahead of print) | author = Alexander Shulgin | coauthor = Ann Shulgin | accessdate = April 2010}}</ref> Relative to the other tryptamine psychedelics, DALT and [[5-MeO-DALT]] are said to be much weaker and far more gentle in comparison.<ref name="urlThe Psychedelic Index - DALT (ahead of print)">{{cite web | url = http://www.bluelight.ru/vb/showpost.php?p=2104770&postcount=15 | title = The Psychedelic Index - DALT (ahead of print) | author = Alexander Shulgin | coauthor = Ann Shulgin | accessdate = April 2010}}</ref><ref name="urlBluelight Forums - The Big & Dandy 5-MeO-DALT Thread - Page 1">{{cite web | url = http://www.bluelight.ru/vb/showthread.php?t=146249 | title = Bluelight Forums - The Big & Dandy 5-MeO-DALT Thread - Page 1 | format = HTML | accessdate = April 2010}}</ref>{{Verify credibility|date=September 2011}} However, if [[smoked]], they may be more comparable to DMT and the like, potentially capable of producing 'breakthrough' experiences.<ref name="urlBluelight Forums - The Big & Dandy 5-MeO-DALT Thread - Page 4">{{cite web | url = http://www.bluelight.ru/vb/showthread.php?t=146249&page=4 | title = Bluelight Forums - The Big & Dandy 5-MeO-DALT Thread - Page 4 | format = HTML | accessdate = April 2010}}</ref>{{Verify credibility|date=September 2011}}
+One of the more pronounced effects of this substance is a sharp increase in body temperature, similar to the effects of 2,4-Dinitrophenol (DNP). Unlike DNP, DALT is suggested to be safer, as it belongs to the tryptamine family. DALT exhibits weak psychoactive properties, particularly among tryptamines.
+The metabolic effects of this substance on body temperature, and its non-toxic nature, leads to the viability of this substance being used for emergency situations in cold weather environments, or as a weight loss supplement.{{Citation needed|date=August 2023}}
 == See also ==
+* [[4-AcO-DALT]]
 * [[5-MeO-DALT]]
 == References ==
 {{Reflist}}
-== External links ==
-* [http://isomerdesign.com/PiHKAL/explore.php?domain=tk&id=5372 isomerdesign.com - N,N-Diallyltryptamine (DALT)]
 {{Hallucinogens}}
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 [[Category:Psychedelic tryptamines]]
+[[Category:Designer drugs]]
 [[Category:Entheogens]]
-[[Category:Alkenes]]
+[[Category:Allyl compounds]]