USS Comfort may refer to the following ships operated by the United States:
- USS Comfort (AH-3), a hospital ship, was acquired in 1917 and served until 1921
- USS Comfort (AH-6), the lead ship of the Comfort-class hospital ship, which served from 1944 until 1946
- USNS Comfort (T-AH-20), a Mercy-class hospital ship, which began its service in 1987
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.