Swanee may refer to:
- Suwannee River, re-spelled "Swanee" by Stephen Foster to fit the rhythm in "Old Folks at Home", influencing subsequent uses of the word, such as:
- "Swanee" (song), a song by George Gershwin and Irving Caesar, made popular by Al Jolson
- Slide whistle, also called a swanee whistle
- Swanee, a soft drink made by the defunct Bob's-Cola company
- Swanee (singer), the stage name of John Swan, an Australian rock singer