English: Marburg virion structure and genome organization. Above, schematic of Marburg virion. Below, structure of the MARV genome with transcription signals. The colors of the open reading frames correspond to the colors of the viral proteins. Untranslated regions of the different genes are shown as light grey boxes; intergenic regions (IR) are shown as dark grey lines and the leader and trailer of the genome are colored in black. Transcription start signals (Tc start) are represented by green triangles, while transcription stop signals (Tc stop) are shown as red bars. The sequence of two gene borders (NP/VP35 and VP30/VP24) is shown in 3’ to 5’ orientation, as it occurs in the negative sense RNA genome (MARV Musoke, GenBank accession number: NC_001608). The gene border between VP30 and VP24 contains overlapping transcription signals, with the start signal of VP24 upstream of the stop signal of VP30.