Issue 5, 2011
From the journal:

Chemical Society Reviews

Recent advances in molecular imprinting technology: current status, challenges and highlighted applications

Lingxin Chen,*a   Shoufang Xuab  and  Jinhua Lia  

* Corresponding authors

a Key Laboratory of Coastal Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China
E-mail: [email protected]
Fax: +86-535-2109130
Tel: +86-535-2109130

b Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Abstract

Molecular imprinting technology (MIT) concerns formation of selective sites in a polymer matrix with the memory of a template. Recently, molecularly imprinted polymers (MIPs) have aroused extensive attention and been widely applied in many fields, such as solid-phase extraction, chemical sensors and artificial antibodies owing to their desired selectivity, physical robustness, thermal stability, as well as low cost and easy preparation. With the rapid development of MIT as a research hotspot, it faces a number of challenges, involving biological macromolecule imprinting, heterogeneous binding sites, template leakage, incompatibility with aqueous media, low binding capacity and slow mass transfer, which restricts its applications in various aspects. This critical review briefly reviews the current status of MIT, particular emphasis on significant progresses of novel imprinting methods, some challenges and effective strategies for MIT, and highlighted applications of MIPs. Finally, some significant attempts in further developing MIT are also proposed (236 references).

Graphical abstract: Recent advances in molecular imprinting technology: current status, challenges and highlighted applications

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C0CS00084A
Article type
Critical Review
Submitted
18 Aug 2010
First published
28 Feb 2011

Chem. Soc. Rev., 2011,40, 2922-2942

Permissions

Request permissions

Recent advances in molecular imprinting technology: current status, challenges and highlighted applications

L. Chen, S. Xu and J. Li, Chem. Soc. Rev., 2011, 40, 2922 DOI: 10.1039/C0CS00084A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements