Issue 95, 2015
From the journal:

RSC Advances

Fabrication of paper-based microfluidic analysis devices: a review

Yong He,ab   Yan Wu,ab   Jian-Zhong Fu*ab  and  Wen-Bin Wuab  

* Corresponding authors

a The State Key Lab of Fluid Power Transmission and Control, College of Mechanical Engineering, Zhejiang University, Hangzhou 310027, China
E-mail: [email protected]

b Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province, College of Mechanical Engineering, Zhejiang University, Hangzhou 310027, China

Abstract

When compared with conventional microfluidic chips made of glass and polymer substrates, paper-based microfluidic analysis devices (μPADs) possess many unique advantages, including low-cost, easy-to-fabricate, strong capillary action and good biological compatibility. In recent years, μPADs have attracted increased interest and attention, which has led to their rapid development. Thousands of literature reports regarding μPADs have been published and a variety of μPADs fabrication methods have been reported. This review focuses on the development of the fabrication methods of 2D and 3D μPADs since 2007. A summary of the advantages and disadvantages of these methods is provided with particular attention paid to the resolution and cost of each method. Suitable applications of each method are discussed. Also, some trends of μPADs are summarized.

Graphical abstract: Fabrication of paper-based microfluidic analysis devices: a review

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Article information

DOI
https://doi.org/10.1039/C5RA09188H
Article type
Review Article
Submitted
17 May 2015
Accepted
04 Sep 2015
First published
07 Sep 2015

RSC Adv., 2015,5, 78109-78127

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Fabrication of paper-based microfluidic analysis devices: a review

Y. He, Y. Wu, J. Fu and W. Wu, RSC Adv., 2015, 5, 78109 DOI: 10.1039/C5RA09188H

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