Towards an Evolutionary Model of Transcription Networks
Figure 5
Re-wiring rate against divergence time.
(A) Re-wiring rate against phylogenetic distance. Circles: Gata3/Gata4/Gata6 genes. Cross: cMyc(MYC)/nMyc(MYCN) genes. TreeFam branch length of a gene is the distance between the speciation event of the gene and the first duplication event in the paralogous family. (B, C) Phylogenetic trees of the Gata and the Myc families in mammals. Blue dot: gene speciation event. Red dot: gene duplication event. Branch lengths are estimated for the consensus tree of bootstrapped trees using HKY model. Numbers on branching events are the support numbers to the consensus tree in 100 bootstrapped trees.
doi: https://doi.org/10.1371/journal.pcbi.1002064.g005