Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
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Evidence for Brain Activation in Patients With Takotsubo Cardiomyopathy
Hideaki Suzuki, Yasuharu Matsumoto, Tomohiro Kaneta, Koichiro Sugimura, Jun Takahashi, Yoshihiro Fukumoto, Shoki Takahashi, Hiroaki Shimokawa
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Keywords: Brain, SPECT, Stress, Takotsubo cardiomyopathy
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2014 Volume 78 Issue 1 Pages 256-258

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Abstract
Background: It remains to be elucidated whether brain activity is altered in takotsubo cardiomyopathy. Methods and Results: We measured cerebral blood flow (CBF) in 3 consecutive patients with takotsubo cardiomyopathy using 99mTc ethyl cysteinate dimmer single photon-emission computed tomography (SPECT) in the acute and chronic phases. In all patients, CBF was significantly increased in the hippocampus, brainstem and basal ganglia and significantly decreased in the prefrontal cortex in the acute phase, which changes subsided in the chronic phase with full recovery of cardiac wall motion. Conclusions: These results provide the first direct evidence for brain activation in takotsubo cardiomyopathy.  (Circ J 2014; 78: 256–258)
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© 2014 THE JAPANESE CIRCULATION SOCIETY
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The Nippon Journal of Clinical Angio-Cardiology

Japanese Circulation Journal

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