Simultaneous recovery of chromophore concentrations and ultrasound velocity by spectrally resolved photoacoustic tomography

Zhen Yuan; Qizhi Zhang; Stephen Grobmyer; Huabei Jiang

doi:10.1117/12.809499

12 February 2009 Simultaneous recovery of chromophore concentrations and ultrasound velocity by spectrally resolved photoacoustic tomography

Zhen Yuan, Qizhi Zhang, Stephen Grobmyer, Huabei Jiang

Author Affiliations +

Proceedings Volume 7177, Photons Plus Ultrasound: Imaging and Sensing 2009; 71770Y (2009) https://doi.org/10.1117/12.809499
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

We describe a new spectral approach for inversion of photoacoustic data with multi-wavelength pulsed laser illumination. Multi-spectral PAT provides a means of recovery of different chromophore concentrations and ultrasound velocity simultaneously and directly by incorporating prior spectral information into the image reconstruction process. It is demonstrated from simulation tests and small animal experiments that the multi-parameter recovery based on multispectral PAT is reliable and accurate. The reconstructed multiple parameter images may provide us a key tool to quantify physiological function, disease progression, or response to intervention.

Citation Download Citation

Zhen Yuan, Qizhi Zhang, Stephen Grobmyer, and Huabei Jiang "Simultaneous recovery of chromophore concentrations and ultrasound velocity by spectrally resolved photoacoustic tomography", Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770Y (12 February 2009); https://doi.org/10.1117/12.809499

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