Feasibility of 4D HDR brachytherapy source tracking using C-arm tomography: Monte Carlo investigation

Roman Vasyltsiv; Xin Qian; Zhigang Xu; Samuel Ryu; Wei Zhao; Adrian Howansky

doi:10.1117/12.2611907

4 April 2022 Feasibility of 4D HDR brachytherapy source tracking using C-arm tomography: Monte Carlo investigation

Roman Vasyltsiv, Xin Qian, Zhigang Xu, Samuel Ryu, Wei Zhao, Adrian Howansky

Proceedings Volume 12034, Medical Imaging 2022: Image-Guided Procedures, Robotic Interventions, and Modeling; 120340H (2022) https://doi.org/10.1117/12.2611907
Event: SPIE Medical Imaging, 2022, San Diego, California, United States

Abstract

High dose rate (HDR) brachytherapy is a standard radiation therapy for skin, vaginal, cervical, uterine and prostate cancers. Currently, there are few practical approaches to tracking HDR source position in vivo due to dose, shielding, accessibility and workflow challenges, hence internal dosimetry typically cannot be directly verified. Accurate source tracking capabilities are desired to reduce uncertainty in the delivered versus planned treatment dose, which may limit underdose and overdose of the prescribed treatment volume and healthy tissues and improve clinical outcomes. This work investigates the feasibility of using an isocentric C-arm x-ray imaging system to achieve 4D HDR brachytherapy source tracking in vivo using cone-beam tomography and highly constrained reconstruction methods. Monte Carlo simulations using the MC-GPU platform and XCAT anthropomorphic phantom were performed to simulate the imaging workflow for such a system, and investigate the impact of detector, image acquisition and reconstruction parameters on its achievable spatiotemporal resolution. Tradeoffs in the system’s spatial, temporal, and dose characteristics are determined. The results indicate that 4D resolutions on the order of 1 mm and 1-2 second may be achieved, which is acceptable for all current HDR brachytherapy applications.

Conference Presentation

Citation Download Citation

Roman Vasyltsiv, Xin Qian, Zhigang Xu, Samuel Ryu, Wei Zhao, and Adrian Howansky "Feasibility of 4D HDR brachytherapy source tracking using C-arm tomography: Monte Carlo investigation", Proc. SPIE 12034, Medical Imaging 2022: Image-Guided Procedures, Robotic Interventions, and Modeling, 120340H (4 April 2022); https://doi.org/10.1117/12.2611907

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available