KLK5

KLK5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2PSX, 2PSY
Dynodwyr
Cyfenwau	KLK5, KLK-L2, KLKL2, SCTE, kallikrein related peptidase 5
Dynodwyr allanol	OMIM: 605643 HomoloGene: 75000 GeneCards: KLK5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • hydrolase activity • GO:0070122 peptidase activity • serine-type peptidase activity • endopeptidase activity • serine-type endopeptidase activity Cydrannau o'r gell • epidermal lamellar body • extracellular region • extracellular space • cytosol • secretory granule Prosesau biolegol • positive regulation of antibacterial peptide production • positive regulation of G protein-coupled receptor signaling pathway • proteolysis • epidermis development • cornification • extracellular matrix disassembly • amelogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	25818	n/a
Ensembl	ENSG00000167754	n/a
UniProt	Q9Y337	n/a
RefSeq (mRNA)	NM_001077491 NM_001077492 NM_012427	n/a
RefSeq (protein)	NP_001070959 NP_001070960 NP_036559	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KLK5 yw KLK5 a elwir hefyd yn Kallikrein related peptidase 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19q13.41.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KLK5.

• SCTE
• KLKL2
• KLK-L2

Llyfryddiaeth

• "Upregulation of kallikrein‑related peptidase 5 is associated with the malignant behavior of colorectal cancer. ". Mol Med Rep. 2016. PMID 27430713.
• "Human kallikrein 5 as a novel prognostic biomarker for triple-negative breast cancer: tissue expression analysis and relationship with disease course. ". Genet Mol Res. 2015. PMID 26345898.
• "Decreased plasma kallikrein 5 concentrations in patients with chronic spontaneous urticaria. ". J Biol Regul Homeost Agents. 2017. PMID 28685545.
• "Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs. ". J Virol. 2017. PMID 28615200.
• "Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity.". J Allergy Clin Immunol. 2017. PMID 28238749.