inSEIT

Erneut durften wir vergangenen Mittwoch den Unternehmer helfen Jungunternehmern Event bei uns im Office in Bern hosten! 🎉 Der Abend startete mit einem inspirierenden Welcome Speech von Dr. Heiko Visarius, der uns auch als Moderator durch das Programm führte. Ein Highlight war die beeindruckende Gründerstory von Mike Kurt, der uns Einblicke in seine Reise vom Olympiasportler zum Unternehmer bei #ibelieveinyou gab. 🌟 Vier innovative Start-ups hatten die Chance, ihre spannenden Projekte vorzustellen: Yossi Bar von LEM Surgical AG zeigte uns die neuesten Entwicklungen in der robotischen Wirbelsäulenchirurgie. David Roura Padrosa, PhD von inSEIT präsentierte einen Durchbruch in der Medikamentenherstellung, der bereits grosse kommerzielle Fortschritte macht. Jürg Germann von Inverto Earth sprach über ihre Mission, unsere Küstenlandschaften wiederherzustellen. Theresa Zanganeh von OiOiOi stellte eine nachhaltige Lösung für den Kauf von Babybekleidung vor, die Ressourcen schont. Pascal Grossniklaus von ahead AG, ein Alumni dieses Events, erzählte abschliessend, wie sich sein Unternehmen seit seiner letzten Teilnahme weiterentwickelt hat und welche Erfolge erzielt wurden. Zur Krönung des Abends gab es ein leckeres Apéro und die perfekte Gelegenheit für Networking. 🍷🤝 Schau dir die Bilder an, um einen Einblick in diesen inspirierenden Abend zu bekommen! #Networking #Entrepreneurship #Innovation #Startups #EventRecap

Happy 2nd Birthday, inSEIT! 🎉 Last monday marked two years of innovation, collaboration, and pushing the boundaries of sustainable biocatalysis! 🌱 We’ve grown into a team dedicated to making enzyme immobilization smarter, greener, and more efficient. We couldn't have come this far without the support of our amazing team and partners—thank you! Looking forward to many more years of transforming the biotech industry with our passion for sustainability and technological excellence. 🚀 Here’s to more breakthroughs and more cake! 🎂 #HappyBirthday #TeamInSEIT #SustainableBiotech #Innovation #EnzymeImmobilization #GreenChemistry #Biocatalysis

✨ 𝐍𝐞𝐰 𝐇𝐢𝐠𝐡𝐥𝐢𝐠𝐡𝐭 ✨ Title: Microtiter Plate Immobilization Screening for Prototyping Heterogeneous Enzyme Cascades Authors: López, IL; Sánchez-Costa, M; Orrego, AH; Zeballos, N; Roura Padrosa, D; López-Gallego, F. Journal: Angew. Chem. Int. Ed, 2024. DOI: 10.1002/anie.202407411 Immobilization is a key enabling technology in applied biocatalysis that facilitates the separation, recovery, and reuse of heterogeneous biocatalysts. However, finding a consensus immobilization protocol for several enzymes forming a multi-enzyme system is extremely difficult and relies on a combinatorial trial-and-error approach. Herein, we describe a protocol in which 17 different carriers functionalized with different reactive groups are tested in a 96-well microtiter plate to screen up to 21 immobilization protocols for up to 18 enzymes. This screening includes an activity and stability assay to select the optimal immobilization chemistry to achieve the most active and stable heterogeneous biocatalysts. The information retrieved from the screening can be rationalized using a Python-based application CapiPy. Finally, through scoring the screening results, we find the consensus immobilization protocol to assemble an immobilized four-enzyme system to transform vinyl acetate into (S)-3-hydroxybutyric acid. This methodology opens a path to speed up the prototyping of immobilized multi-enzyme pathways for chemical manufacturing. Más información 👉 : https://lnkd.in/dYKcUzY6 DOI: 10.1002/anie.202407411 Fernando López Gallego inSEIT

Two years ago today, David Roura Padrosa, PhD, Francesca Paradisi and I embarked on this amazing journey with the creation of inSEIT, with our aim being to facilitate the transition of the chemical industry towards a more sustainable way of manufacturing. Over the past two years we have worked with several companies to immobilize enzymes for their processes, speeding up their development at a fraction of the time and normal costs. Recently this year we launched our own catalogue of immobilized enzymes, which we look forward to expanding in the coming years and continuing to work with our clients and growing our team. (Check out our catalogue here, https://lnkd.in/eEbzfUXQ) Together we can make chemical manufacturing more sustainable. Immobilize to go further. 🚀 https://www.inseit.ch/ #sustainability #biocatalysis #immobilization

🌟 Let’s talk about  𝗦𝗘𝗜𝗧𝘇𝘆𝗺𝗲 𝗜𝗺𝗺𝗼𝗯𝗶𝗹𝗶𝘇𝗲𝗱 𝗣𝗲𝗿𝗼𝘅𝗶𝗱𝗮𝘀𝗲𝘀!  🌟 We’re excited to showcase a new section of the SEITzyme catalog: immobilized peroxidases for peroxide detoxification! These ready-to-use biocatalysts are optimized for enhanced stability, high reusability, and efficient separation from reaction mixtures. 🧪✨ 🔑 𝗪𝗵𝗮𝘁’𝘀 𝗶𝗻𝘀𝗶𝗱𝗲? 1️⃣ 𝗖𝗮𝘁𝗮𝗹𝗮𝘀𝗲 (𝗦𝗭-𝗖𝗔𝗧𝟬𝟬𝟭): Efficiently decomposes hydrogen peroxide into water and oxygen, ensuring the removal of reactive oxygen species. 2️⃣ 𝗛𝗼𝗿𝘀𝗲𝗿𝗮𝗱𝗶𝘀𝗵 𝗣𝗲𝗿𝗼𝘅𝗶𝗱𝗮𝘀𝗲 (𝗦𝗭-𝗣𝗘𝗥𝟬𝟬𝟭): Breaks down a wide variety of peroxides, offering high efficiency in detoxifying harmful compounds while also catalyzing oxygen transfer reactions and oxidations for versatile industrial applications. Whether you’re working in  𝗰𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝗺𝗮𝗻𝘂𝗳𝗮𝗰𝘁𝘂𝗿𝗶𝗻𝗴, 𝗲𝗻𝘃𝗶𝗿𝗼𝗻𝗺𝗲𝗻𝘁𝗮𝗹 𝗿𝗲𝗺𝗲𝗱𝗶𝗮𝘁𝗶𝗼𝗻, or other industries, our immobilized peroxidases provide reliable performance and stability. Specifically designed to minimize enzyme leaching, these biocatalysts ensure smooth and safe industrial operations. 📩 Want to learn more? Scan the QR code in the carousel, contact us at [email protected], or visit our website for the full catalog at inseit.ch/products. 🧬 Need something specific? We offer custom screening and tailored development if the enzyme you’re looking for isn’t listed. Reach out for a quote today! #Sustainability #Enzymes #Peroxidases #IndustrialBiomanufacturing #inSEIT #Innovation #Biotechnology #PeroxideDetoxification #ImmobilizedEnzymes

🌟 Let’s talk about  𝗦𝗘𝗜𝗧𝘇𝘆𝗺𝗲 𝗜𝗺𝗺𝗼𝗯𝗶𝗹𝗶𝘇𝗲𝗱 𝗣𝗲𝗿𝗼𝘅𝗶𝗱𝗮𝘀𝗲𝘀!  🌟 We’re excited to showcase a new section of the SEITzyme catalog: immobilized peroxidases for peroxide detoxification! These ready-to-use biocatalysts are optimized for enhanced stability, high reusability, and efficient separation from reaction mixtures. 🧪✨ 🔑 𝗪𝗵𝗮𝘁’𝘀 𝗶𝗻𝘀𝗶𝗱𝗲? 1️⃣ 𝗖𝗮𝘁𝗮𝗹𝗮𝘀𝗲 (𝗦𝗭-𝗖𝗔𝗧𝟬𝟬𝟭): Efficiently decomposes hydrogen peroxide into water and oxygen, ensuring the removal of reactive oxygen species. 2️⃣ 𝗛𝗼𝗿𝘀𝗲𝗿𝗮𝗱𝗶𝘀𝗵 𝗣𝗲𝗿𝗼𝘅𝗶𝗱𝗮𝘀𝗲 (𝗦𝗭-𝗣𝗘𝗥𝟬𝟬𝟭): Breaks down a wide variety of peroxides, offering high efficiency in detoxifying harmful compounds while also catalyzing oxygen transfer reactions and oxidations for versatile industrial applications. Whether you’re working in  𝗰𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝗺𝗮𝗻𝘂𝗳𝗮𝗰𝘁𝘂𝗿𝗶𝗻𝗴, 𝗲𝗻𝘃𝗶𝗿𝗼𝗻𝗺𝗲𝗻𝘁𝗮𝗹 𝗿𝗲𝗺𝗲𝗱𝗶𝗮𝘁𝗶𝗼𝗻, or other industries, our immobilized peroxidases provide reliable performance and stability. Specifically designed to minimize enzyme leaching, these biocatalysts ensure smooth and safe industrial operations. 📩 Want to learn more? Scan the QR code in the carousel, contact us at [email protected], or visit our website for the full catalog at inseit.ch/products. 🧬 Need something specific? We offer custom screening and tailored development if the enzyme you’re looking for isn’t listed. Reach out for a quote today! #Sustainability #Enzymes #Peroxidases #IndustrialBiomanufacturing #inSEIT #Innovation #Biotechnology #PeroxideDetoxification #ImmobilizedEnzymes

🎉 We’re thrilled to be featured in Swiss Biotech Association latest piece on industrial biotech! At inSEIT, we’re pushing the boundaries of enzyme immobilization with our data-driven, bioinformatics-powered workflows. Our solutions help de-risk biocatalyst development, enhancing compatibility and performance in industrial chemistry. 🌱🔬 Read more here: https://lnkd.in/eBQp6GUR Join us in revolutionizing sustainable chemical production: Immobilized to go further! 💡 #BiotechInnovation #GreenChemistry #IndustrialBiotech #Sustainability

🌿 Join Today our Webinar: “zED Event #5 Immobilize to go further”  co-organized with Aralez Bio🌿 🔬 Explore the future of enzyme immobilization and its potential to revolutionize biocatalysis with two expert-led talks: 1️⃣ David Roura Padrosa, PhD (Co-founder & CEO, inSEIT): "Data-driven Development of Immobilized Enzymes"  2️⃣ Francesca Paradisi (Bern University): "Enzyme Immobilization Enabling Hybrid Catalysis" 🗓 Date: Tuesday, October 15th, 2024 🕒 Time: 8:30 AM PT | 11:30 AM ET | 5:30 PM CET 📍 Platform: Zoom (ZED Event) 🔗 Register in advance here: https://lnkd.in/eH5wHfai After registering, you'll receive a confirmation email with details on how to join. Don’t miss this opportunity to learn how immobilization techniques can advance biocatalysis! #GreenChemistry #EnzymeImmobilization #Biocatalysis #SustainableInnovation #inSEIT #AralezBio #ZEDEvent

✨ What a week at #CPHI2024 in Milan! ✨ Last week I had the opportunity to represent inSEIT at CPHI in Milan. This was my first time attending, and I didn’t know what to expect. It was a fantastic experience—filled with great conversations, exciting insights, and many inspiring people. 🌍💡 Interacting with a variety of professionals from the biotech and chemical industries, passionate about chemistry, biology, and their applications in the pharma and chemical sectors, was a really exciting experience. The event left me with a notebook full of innovative ideas and potential collaborations. A huge thank you to everyone I connected with—you made this the first CPHI to remember. And to the inSEIT team, I’m so proud to have showcased our work in enzyme immobilization on such a global stage! Here’s to new connections, new ideas, and many more events like this in the future. 🚀 #Biotech #Innovation #inSEIT #CPHI2024 #ImmobilizedEnzymes #Sustainability

📢 Join us tomorrow for an exclusive webinar featuring our founders! Discover the latest developments at inSEIT and insights from Francesca Paradisi’s research group. Don’t miss out—sign up now to secure your spot!