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      MitochondriaMitochondrial DNAMitochondrial Dynamics
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      ThermodynamicsInorganic ChemistryProtein FoldingKinetics
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      MultidisciplinaryHematopoiesisAcute Myeloid LeukemiaCell Differentiation
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      ImmunologyAgingApoptosisHematopoiesis
MicroRNAs have emerged as key regulators of B cell fate decisions and immune function. Deregulation of several microRNAs in B cells leads to the development of autoimmune disease and cancer in mice. We demonstrate that the... more
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    • Experimental Medicine
MicroRNAs (miRNAs) are crucial post-transcriptional regulators of haematopoietic cell fate decisions. They act by negatively regulating the expression of key immune development genes, thus contributing important logic elements to the... more
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      ImmunologyHematopoietic Stem CellsmicroRNAs
Abstract During normal vision, when subjects attempt to fix their gaze on a small stimulus feature, small fixational eye movements persist. We have recorded the impulse activity of single neurons in primary visual cortex (V1) of macaque... more
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For optimal response selection, the consequences associated with behavioral success or failure must be appraised. To determine how monetary consequences influence the neural representations of motor preparation, human brain activity was... more
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Abstract This chapter summarizes experiments which were designed to reveal how repetitive electrical stimulation of the mesencephalic locomotor region (MLR) recruits nearby hindbrain neurons into activity, such that locomotion can ensue... more
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The majority of neurons in monkey primary visual cortex (V1) have overlapping increment and decrement activating regions (ARs) and diverse nonlinear properties (" duplex" cells). However, many of these cells, unlike the" classical... more
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ABSTRACT We have previously shown that most cells in the alert monkey V1 are complex cells with overlapping increment and decrement activating regions and nonlinear response properties. Diverse responses of these cells to drifting... more
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Abstract. Cortical complex cells are usually described as nonlinear energy operators that sum squared outputs of quadrature pairs of linear subunits, responding to drifting sinusoidal gratings with unmodulated elevation of firing rate (F0... more
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      Caenorhabditis elegansProtein-DNA interactionYeast one-hybrid
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      Caenorhabditis elegansBiologyTranscription FactorsDNA-binding proteins
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      Caenorhabditis elegansTranscription FactorsDNA-binding proteinsBasic Helix Loop Helix (bHLH) DNA-binding domain
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      Evolutionary BiologyCaenorhabditis elegansTranscription FactorsGene expression