HeartBeat.bio (HBB) is an emerging TechBio company developing a next-generation drug discovery platform for heart diseases. Our so-called Cardioid Drug Discovery Platform is based on a proprietary iPSC-derived single and multi-chamber cardiac organoid model. We combine this unique human biology with state-of-the-art hardware solutions to industrialize the organoid cultivation and screening process as well as AI-supported software for high-content and big data analysis.
HBB pursues an end-to-end human-centric drug discovery approach along the entire pre-clinical value chain: Starting with target identification and validation, disease modeling, hit identification and confirmation, leading up to compound development and profiling as well as dose finding and clinical trials-in-a-dish applications for patient segmentation and clinical trial design. With this human-data driven approach, we expect to overcome the current bottlenecks in preclinical drug discovery and thus develop drugs faster, more cost-effectively and with a higher probability of success.
HBB is focused on Heart Failure which is a severe condition with a high medical need and a significant lack of innovation affecting more than 30 million people in the major pharmaceutical markets. We plan to build a broad portfolio of self-funded and partnered pre-clinical assets within a reasonable time frame of 3-5 years. Initially, the HBB drug discovery program is centered on various types of drug-induced and genetic cardiomyopathies. Programs for post-myocardial infarction therapy, cardiac remodeling and regeneration will follow along with ongoing business development activities.
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Branche
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Biotechnologieforschung
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Größe
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11–50 Beschäftigte
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Hauptsitz
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Vienna
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Art
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Privatunternehmen
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Gegründet
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2021
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Spezialgebiete
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Cardiac Organoids, Human 3D Disease Modelling , High-Throughput Drug Discovery Platform, Cardiac Drug Discovery, Heart Failure, Cardiomyopathy, Heart Regeneration, Myocardial Infarction, Cardiotoxicity, Cardio-Oncology und iPS Cells