Structural studies of CV-70 polysaccharide

Int J Biol Macromol. 1997 Aug;21(1-2):115-21. doi: 10.1016/s0141-8130(97)00050-0.

Abstract

The goal of this paper is the characterization of the chemical structure of the water-soluble polysaccharide, CV-70, produced by bacteria Beijerinckia sp. Beijerinckia sp. is a genus of gram-negative, aerobic bacteria, usually found in sugar cane root. The CV-70 polysaccharide was produced in a fermentation medium containing 5% sucrose as the carbon source, tryptose and salts, at 25 degrees C [1]. The polysaccharide was hydrolyzed with 2 N trifluoroacetic acid at 100 degrees C for 16 h, purified, and analyzed by HPLC. Index of refraction was used for the detection of sugars. For GC-MS analysis, the CV-70 polysaccharide was derivatized through methylation and acetylation. Together with the GC-MS data, periodate oxidation studies were used to determine the possible glucosidic linkages. Carbon-13 NMR studies were carried out with hydrolyzed and silylated samples. Glucose, galactose and fucose were identified as the components in the CV-70 polysaccharide, in a 3:1:3 ratio.

MeSH terms

  • Bacteria / chemistry
  • Carbohydrate Conformation
  • Chromatography, High Pressure Liquid / methods
  • Magnetic Resonance Spectroscopy / methods
  • Mass Spectrometry / methods
  • Monosaccharides / analysis
  • Polysaccharides, Bacterial / chemistry*
  • Polysaccharides, Bacterial / metabolism

Substances

  • Monosaccharides
  • Polysaccharides, Bacterial