Health disparities reflect inequalities in health outcomes among different populations. As a planning tool for researchers and practitioners to address health disparities, multiple frameworks utilizing social determinants of health have been proposed. Perceived behavioral control, a construct within the Integrative Behavioral Model, reflects how much control one feels over a health behavior and how easy or difficult the behavior is to enact under internal and external barriers. The purpose of this commentary is to suggest how a unified social determinant of health framework can be utilized as a predictor and determinant of the construct perceived behavioral control.