Controlling Hydrogel Mechanics via Bio-Inspired Polymer-Nanoparticle Bond Dynamics

ACS Nano. 2016 Jan 26;10(1):1317-24. doi: 10.1021/acsnano.5b06692. Epub 2016 Jan 7.

Abstract

Interactions between polymer molecules and inorganic nanoparticles can play a dominant role in nanocomposite material mechanics, yet control of such interfacial interaction dynamics remains a significant challenge particularly in water. This study presents insights on how to engineer hydrogel material mechanics via nanoparticle interface-controlled cross-link dynamics. Inspired by the adhesive chemistry in mussel threads, we have incorporated iron oxide nanoparticles (Fe3O4 NPs) into a catechol-modified polymer network to obtain hydrogels cross-linked via reversible metal-coordination bonds at Fe3O4 NP surfaces. Unique material mechanics result from the supra-molecular cross-link structure dynamics in the gels; in contrast to the previously reported fluid-like dynamics of transient catechol-Fe(3+) cross-links, the catechol-Fe3O4 NP structures provide solid-like yet reversible hydrogel mechanics. The structurally controlled hierarchical mechanics presented here suggest how to develop hydrogels with remote-controlled self-healing dynamics.

Keywords: bio-inspired metal-coordinate polymers; nanocomposite hydrogels; organic−inorganic interface; polymer physics; rheology; supra-molecular assembly.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Biomimetic Materials / chemistry
  • Bivalvia / chemistry
  • Catechols / chemistry*
  • Elasticity
  • Ferrosoferric Oxide / chemistry*
  • Hydrogels / chemistry*
  • Iron / chemistry*
  • Molecular Structure
  • Nanocomposites / chemistry*
  • Nanocomposites / ultrastructure
  • Nanoparticles / chemistry*
  • Nanoparticles / ultrastructure
  • Pliability
  • Rheology

Substances

  • Catechols
  • Hydrogels
  • Iron
  • Ferrosoferric Oxide