AmiGO 2: Term Details for "gap junction channel activity" (GO:0005243)

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Term Information

Accession: GO:0005243
Name: gap junction channel activity
Ontology: molecular_function
Synonyms: innexin channel activity, connexin, innexin, intercellular channel
Alternate IDs: GO:0015285, GO:0015286
Definition: A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes. Source: GOC:mtg_transport, ISBN:0815340729, GOC:dgh
Comment: None
History: See term history for GO:0005243 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to gap junction channel activity (excluding "regulates").; Link to all direct and indirect annotations to gap junction channel activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for gap junction channel activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment of localization
GO:0009987 cellular process
GO:0003674 molecular_function
GO:0006810 transport
GO:0055085 transmembrane transport
GO:0005215 transporter activity
GO:0022857 transmembrane transporter activity
GO:0022803 passive transmembrane transporter activity
GO:0015267 channel activity
GO:0022829 wide pore channel activity
GO:0005243 gap junction channel activity
GO:1903763 gap junction channel activity involved in cell communication by electrical coupling
GO:0055077 gap junction hemi-channel activity

Parents of gap junction channel activity (GO:0005243)

subject	relation	object
gap junction channel activity	is_a	wide pore channel activity (GO:0022829)

Children of gap junction channel activity (GO:0005243)

subject	relation	object
gap junction channel activity involved in cell communication by electrical coupling (GO:1903763)	is_a	gap junction channel activity
gap junction hemi-channel activity (GO:0055077)	BFO:0000050	gap junction channel activity

Reactome: R-HSA-190681; R-HSA-375339; R-HSA-375330; R-HSA-375340; R-HSA-375342