Janus kinase 1 (Q6155967)

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mammalian protein found in Homo sapiens
  • tyrosine-protein kinase JAK1
  • JAK1
  • JAK-1
edit
Language Label Description Also known as
English
Janus kinase 1
mammalian protein found in Homo sapiens
  • tyrosine-protein kinase JAK1
  • JAK1
  • JAK-1

Statements

part of
molecular function
protein binding
determination method or standard
IPI
5 references
retrieved
8 April 2019
stated in
Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor
GOA
curator
UniProt
UniProt protein ID
P23458
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
IPI
retrieved
8 April 2019
stated in
CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
IPI
retrieved
8 April 2019
stated in
Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
IPI
retrieved
8 April 2019
stated in
A quantitative protein interaction network for the ErbB receptors using protein microarrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
IPI
retrieved
8 April 2019
stated in
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
IPI
protein tyrosine kinase activity
determination method or standard
EXP
TAS
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
TAS
retrieved
8 April 2019
stated in
Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P23458
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
IEA
retrieved
8 April 2019
stated in
Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
EXP
retrieved
8 April 2019
stated in
The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
EXP
retrieved
8 April 2019
stated in
A protein tyrosine kinase in the interferon alpha/beta signaling pathway
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23458
determination method or standard
EXP
cell component
biological process
physically interacts with
Gene Atlas image
PBB GE JAK1 201648 at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
D053613
subject named as
Janus Kinase 1
0 references
PDB structure ID
 
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