Search Results (5,321)

Background/Objectives: Physical activity is an important protective factor throughout life. However, little research has observed the associations between the practice of physical activity and academic success longitudinally, and none have done so with a pan-Canadian sample. This article aims to examine the prospective associations between active leisure in middle childhood and academic achievement in emerging adulthood, for both boys and girls, beyond several family factors. Methods: Participants are 2775 children from the National Longitudinal Study on Children and Youth (NLSCY) aged between 12 and 20 years. Active leisure was self-reported by children at age 12 years regarding their weekly organized sport, artistic sport, and unstructured physical activity participation outside of school hours. Academic success was measured by self-reported school average at age 18 years and the obtention of high school diploma at age 20 years. Results: Girls who engaged in more organized or artistic sports at age 12 years had better academic results at age 18 years (respectively β = −0.082, p < 0.01; β = −0.228, p < 0.001). Both boys and girls who partook in more organized sports at age 12 years were more likely to graduate from high school by age 20 years (respectively β = −0.146, p < 0.001; β = −0.071, p < 0.05). However, girls who engaged in more unstructured physical activity at age 12 years had lower academic achievement at age 18 years (β = 0.077, p < 0.001). Conclusions: Policy makers should aim to reduce the many barriers to an active lifestyle in childhood. Parents should be encouraged to lead their children to go play outside with friends to allow them to fully reap the benefits of an active lifestyle from a young age. Full article

Food security is threatened by climate change and associated abiotic stresses that affect the flowering stage and the biochemistry of flowers and fruits. In tomato, managed insect pollination and grafting elite tomato varieties onto robust rootstocks are widely practiced commercially to enhance tomato crop profitability, particularly under suboptimal conditions. However, little is known about rootstock–pollinator interactions and their impact on the chemical composition of fruit. In this study, a commercial tomato F1 hybrid (Solanum lycopersicum L.) was self-grafted and grafted onto a set of experimental rootstocks and cultivated under optimal and saline (75 mM NaCl) conditions in the presence of managed bumblebee pollinators (Bombus terrestris). The number of visits (VN) and total visiting time (TVT) by pollinators to different grafted plants were monitored through an RFID (radio-frequency identification) tracking system, while targeted metabolites (hormones, sugars, and organic and amino acids) and mineral composition were analyzed in the fruit juice by UHPLC-MS and ICP-OES, respectively. Pollinator foraging decisions were influenced by the rootstocks genotype and salinity treatment. Experimental rootstocks predominantly increased pollinator attraction compared to the self-grafted variety. Interestingly, the pollinator parameters were positively associated with the concentration of abscisic acid, salicylic acid, malate and fumarate, and tyrosine in salinized fruits. Moreover, a high accumulation of sodium was detected in the fruits of the plants most visited by pollinators, while rootstock genotype-specific responses were found for nitrogen and potassium concentrations. In addition to the known effect on yield, these findings underscore the synergic interactions between rootstocks, pollinators, and environmental stressors on tomato fruit composition. Full article

Histiocytoses are rare diseases characterised by infiltration of affected organs by myeloid cells with a monocyte or dendritic cell phenotype. Symptoms can range from self-resolving localised forms to multisystemic lesions requiring specific treatment. To demonstrate extremely rare cases of CD68-negative cardiac histiocytosis with expression of SARS-CoV-2 antigen in infiltrate cells. We demonstrated a case of Erdheim–Chester disease in a 67-year-old man with pericardial involvement and positive dynamics with vemurafenib treatment, an autopsy case of xanthogranulomatous myopericarditis in a 63-year-old man, surgical material of xanthogranulomatous constrictive pericarditis in a 57-year-old man, and an autopsy case of xanthogranulomatosis in a 1-month-old girl. In all cases, xanthogranuloma cells expressed CD163, many of them spike protein SARS-CoV-2, while CD68 expression was detected only in single cells. In this article, we demonstrated four cases of extremely rare CD68-negative cardiac xanthogranulomatosis in three adults and one child with expression of the spike protein SARS-CoV-2 in M2 macrophages. This potential indirect association between COVID-19 and the development of histiocytosis in these patients warrants further investigation. To substantiate this hypothesis, more extensive research is needed. Full article

Solid-state electrolytes (SSEs), particularly garnet-type Li_6.4La₃Zr_1.4Ta_0.6O₁₂ (LLZTO), offer high stability and a wide electrochemical window. However, their grain boundaries limit ionic conductivity, necessitating high-temperature sintering for improved performance. Yet, this process results in brittle electrolytes prone to fracture during manufacturing. To address these difficulties, solvent-free solid-state electrolytes with a polyacrylonitrile (PAN) coating on LLZTO particles are reported in this work. Most notably, the PAN-coated LLZTO (PAN@LLZTO) electrolyte demonstrates self-supporting characteristics, eliminating the need for high-temperature sintering. Importantly, the homogeneous polymeric PAN coating, synthesized via the described method, facilitates efficient Li⁺ transport between LLZTO particles. This electrolyte not only achieves an ionic conductivity of up to 2.11 × 10⁻³ S cm⁻¹ but also exhibits excellent interfacial compatibility with lithium. Furthermore, a lithium metal battery incorporating 3% PAN@LLZTO-3%PTFE as the solid-state electrolyte and LiFePO₄ as the cathode demonstrates a remarkable specific discharge capacity of 169 mAh g⁻¹ at 0.1 °C. The strategy of organic polymer-coated LLZTO provides the possibility of a green manufacturing process for preparing room-temperature sinter-free solid-state electrolytes, which shows significant cost-effectiveness. Full article

The concept of intelligence has many applications, such as in coatings and cyber security. Smart coatings have the ability to sense and/or respond to external stimuli and generally interact with their environment. Self-healing coatings represent a significant advance in improving material durability and performance using microcapsules and nanocontainers loaded with self-healing agents, catalysts, corrosion inhibitors, and water-repellents. These smart coatings can repair damage on their own and restore mechanical properties without external intervention and are inspired by biological systems. Properties that are affected by either momentary or continuous external stimuli in smart coatings include corrosion, fouling, fungal, self-healing, piezoelectric, and microbiological properties. These coating properties can be obtained via combinations of either organic or inorganic polymer phases, additives, and pigments. In this article, a review of the advancements in micro/nanocapsules for self-healing coatings is reported from the aspect of extrinsic self-healing ability. The concept of extrinsic self-healing coatings is based on the use of capsules or multichannel vascular systems loaded with healing agents/inhibitors. The result is that self-healing coatings exhibit improved properties compared to traditional coatings. Self-healing anticorrosive coating not only enhances passive barrier function but also realizes active defense. As a result, there is a significant improvement in the service life and overall performance of the coating. Future research should be devoted to refining self-healing mechanisms and developing cost-effective solutions for a wide range of industrial applications. Full article

Persona, a special means of image management by social media influencers (SMIs), has become a trending phenomenon and it is expected to substantially affect SMIs’ persuasiveness and ad effect. This study aims to explore the impact of SMIs’ personas constructed through personal values on the effectiveness of social media video ads. Adopting the Stimulus-Organism-Response (S-O-R) framework, this study validates how SMIs’ personas constructed through self-enhancement values and self-transcendence values affect consumer cognitive processes and responses. Consumer behavioral intentions are used to verify the effectiveness of ads derived by SMIs. The findings reveal that influencers’ personas constructed by values can promote consumer purchase intention and forwarding intention. Consumer perceptions of self (i.e., ideal self and actual self) have a mediating role. Results also show that SMIs’ personas with self-enhancement values are more effective in stimulating female consumers’ forwarding intention, whereas personas with self-transcendence values are more influential in female consumers’ purchase intention. This study enriches the influencer marketing literature by providing a more tailored understanding of the impact of SMIs’ personas and extending the applicability of value theory. It also provides insights for stakeholders involved in influencer marketing on how to significantly capitalize on the benefits and deploy marketing campaigns. Full article

During a ship’s voyage, it is difficult to maintain its hull, and prolonged exposure to seawater can lead to the attachment of marine organisms, which can negatively impact the ship’s speed. The original self-polishing copolymer was a tributyltin-containing paint used for applying two layers of protective coating onto a ship’s bottom plate. According to International Maritime Organization (abbreviated as IMO) regulations, users are no longer allowed to use paints containing tributyltin. Therefore, manufacturers have developed a tributyltin-free paint, known as tin-free nanotechnology paint, which can be used as a replacement for the base coat on ship bottom plates. This study involves the use of a self-polishing copolymer spray and tin-free nanotechnology paint. A model coated with these two types of paint will be observed underwater to study the growth of marine organisms. Additionally, fuel consumption will be analyzed through underwater inspections and sea trials. Based on the experimental data, it is known that tin-free nanotechnology paint can significantly reduce the need for repairs in factories and greatly decrease maintenance costs when compared to self-polishing copolymers. Full article

Freedom of movement of the hands is the most desired hope of stroke patients. However, stroke recovery is a long, long road for many patients. If artificial intelligence can assist human arm movement, the possibility of stroke patients returning to normal hand movement might be significantly increased. This study uses the artificial neuromolecular system (ANM system) developed in our laboratory as the core of motion control, in an attempt to learn to control the mechanical arm to produce actions similar to human rehabilitation training and the transition between different activities. This research adopts two methods. The first is hypothetical exploration, the so-called “artificial world” simulation method. The detailed approach uses the V-REP (Virtual Robot Experimentation Platform) to conduct different experimental runs to capture relevant data. Our policy is to establish an action database systematically to a certain extent. From these data, we use the ANM system with self-organization and learning capabilities to develop the relationship between these actions and establish the possibility of conversion between different activities. The second method of this study is to use the data from a hospital in Toronto, Canada. Our experimental results show that the ANM system can continuously learn for problem-solving. In addition, our three experimental results of adaptive learning, transfer learning, and cross-task learning further confirm that the ANM system can use previously learned systems to complete the delivered tasks through autonomous learning (instead of learning from scratch). Full article

Federated Learning (FL) is an emerging privacy-preserving technology that enables training a global model beneficial to all participants without sharing their data. However, differences in data distributions among participants may undermine the stability and accuracy of the global model. To address this challenge, recent research proposes client clustering based on data distribution similarity, generating independent models for each cluster in order to enhance FL performance. Nevertheless, due to the uncertainty of participant identities, FL struggles to rapidly and accurately determine the clusters. Most of the existing algorithms distinguish clients by iterative clustering, which not only increases the computing cost of the server but also affects the convergence speed of the federation model. To address these shortcomings, in this paper, we propose a novel clustering-based FL method, SoFL. SoFL introduces SOM networks, improves the quality of cluster data, and eliminates redundant categories through secondary clustering, encouraging more similar clients to train together. Through this mechanism, SoFL completes the clustering task in one round of communication and speeds up the convergence of federated model training. Simulation results demonstrate that SoFL accurately and swiftly adapts to determine the clusters. In different non-IID settings, SoFL’s model accuracy improvements ranged from 9 to 18% compared to FedAvg and FedProx. Full article

The aim of this study was to develop a material capable of rapidly absorbing bodily fluids and forming a resilient, adhesive, viscoelastic hydrogel in situ to prevent post-surgical adhesions. This material was formulated using O-carboxymethyl chitosan (O-CMCS), oxidized hyaluronic acid (OHA), and a crosslinking pigment derived from genipin and glutamic acid (G/GluP). Both crosslinked (O-CMCS/OHA-G/GluP) and non-crosslinked hydrogels (O-CMCS/OHA) were evaluated using a HAAKE™ MARS™ rheometer for their potential as post-surgical barriers. A rheological analysis, including dynamic oscillatory measurements, revealed that the crosslinked hydrogels exhibited significantly higher elastic moduli (G′), indicating superior gel formation and mechanical stability compared to non-crosslinked hydrogels. The G/GluP crosslinker enhanced gel stability by increasing the separation between G′ and G″ and achieving a lower loss tangent (tan δ < 1.0), indicating robustness under dynamic physiological conditions. The rapid hydration and gelation properties of the hydrogels underscore their effectiveness as physical barriers. Furthermore, the O-CMCS/OHA-G/GluP hydrogel demonstrated rapid self-healing and efficient application via spraying or spreading, with tissue adherence and viscoelasticity to facilitate movement between tissues and organs, effectively preventing adhesions. Additionally, the hydrogel proved to be both cost effective and scalable, highlighting its potential for clinical applications aimed at preventing post-surgical adhesions. Full article

Laboratory medicine has undergone a deep and multifaceted revolution in the course of human history, in both organizational and technical terms. Over the past century, there has been a growing recognition of the need to centralize numerous diagnostic activities, often similar or identical but located in different clinical departments, into a common environment (i.e., the medical laboratory service), followed by a progressive centralization of tests from smaller laboratories into larger diagnostic facilities. Nevertheless, the numerous technological advances that emerged at the beginning of the new millennium have helped to create a new testing culture characterized by a countervailing trend of decentralization of some tests closer to patients and caregivers. The forces that have driven this (centripetal) counter-revolution essentially include a few key concepts, namely “home testing”, “portable or even wearable devices” and “remote patient monitoring”. By their very nature, laboratory medical services and remote patient testing/monitoring are not contradictory, but may well coexist, with the choice of one or the other depending on the demographic and clinical characteristics of the patient, the type of analytical procedure and the logistics and local organization of the care system. Therefore, this article aims to provide a general overview of patient self-testing, with a particular focus on portable and wearable (including implantable) devices. Full article

Aim: Among the severe organ complications occurring in patients with Turner syndrome (TS), ophthalmic dysmorphia and visual impairment are usually marginalized. There are only a few studies that take into account the prevalence of ophthalmic disorders in female patients with TS. Material and methods: Articles in PubMed, Scholar, and Website were reviewed, considering the prevalence of various ocular disorders in patients with X chromosome deficiency. Current standards for the management of patients with TS in the context of the prevalence of ophthalmic disorders were also analyzed. Results: Identification of visual impairment in people is important because it significantly impairs quality of life (QoL) along with other health problems. QoL affects cognitive and behavioral functioning and significantly increases self-esteem, acceptance of treatment, and, consequently, physical and mental health. Low self-esteem makes patients feel helpless and unable to plan their social development. Patients with TS are relatively more frequently diagnosed with various eye defects compared to the healthy population. Therefore, special attention should be paid to the early assessment of the visual system in people with TS to eliminate any factors that could potentially impair their QoL. Conclusions: Patients with TS should be referred to specialist ophthalmologists, pediatricians, or optometrists for preventive care or early treatment of visual impairment. The authors point out the need for comprehensive ophthalmological examinations as standard management in patients with TS. Full article

This paper conducts an in-depth study of a wireless, hierarchical structure-based active balancing system for power batteries, aimed at addressing the rapid advancements in battery technology within the electric vehicle industry. The system is designed to enhance energy density and the reliability of the battery system, developing a balancing system capable of managing cells with significant disparities in characteristics, which is crucial for extending the lifespan of lithium-ion battery packs. The proposed system integrates wireless self-networking technology into the battery management system and adopts a more efficient active balancing approach, replacing traditional passive energy-consuming methods. In its design, inter-group balancing at the upper layer is achieved through a soft-switching LLC resonant converter, while intra-group balancing among individual cells at the lower layer is managed by an active balancing control IC and a bidirectional buck–boost converter. This configuration not only ensures precise control but also significantly enhances the speed and efficiency of balancing, effectively addressing the heat issues caused by energy dissipation. Key technologies involved include lithium-ion batteries, battery management systems, battery balancing systems, LLC resonant converters, and wireless self-networking technology. Tests have shown that this system not only reduces energy consumption but also significantly improves energy transfer efficiency and the overall balance of the battery pack, thereby extending battery life and optimizing vehicle performance, ensuring a safer and more reliable operation of electric vehicle battery systems. Full article

Previously, we described the mechanisms of development of autoimmune encephalomyelitis (EAE) in 3-month-old C57BL/6, Th, and 2D2 mice. The faster and more profound spontaneous development of EAE with the achievement of deeper pathology occurs in hybrid 2D2/Th mice. Here, the cellular and immunological analysis of EAE development in 2D2/Th mice was carried out. In Th, 2D2, and 2D2/Th mice, the development of EAE is associated with a change in the differentiation profile of hemopoietic bone marrow stem cells, which, in 2D2/Th, differs significantly from 2D2 and Th mice. Hybrid 2D2/Th mice demonstrate a significant difference in these changes in all strains of mice, leading to the production of antibodies with catalytic activities, known as abzymes, against self-antigens: myelin oligodendrocyte glycoprotein (MOG), DNA, myelin basic protein (MBP), and five histones (H1–H4) hydrolyze these antigens. There is also the proliferation of B and T lymphocytes in different organs (blood, bone marrow, thymus, spleen, lymph nodes). The patterns of changes in the concentration of antibodies and the relative activity of abzymes during the spontaneous development of EAE in the hydrolysis of these immunogens are significantly or radically different for the three lines of mice: Th, 2D2, and 2D2/Th. Several factors may play an essential role in the acceleration of EAE in 2D2/Th mice. The treatment of mice with MOG accelerates the development of EAE pathology. In the initial period of EAE development, the concentration of anti-MOG antibodies in 2D2/Th is significantly higher than in Th (29.1-fold) and 2D2 (11.7-fold). As shown earlier, antibodies with DNase activity penetrate cellular and nuclear membranes and activate cell apoptosis, stimulating autoimmune processes. In the initial period of EAE development, the concentration of anti-DNA antibodies in 2D2/Th hybrids is higher than in Th (4.6-fold) and 2D2 (25.7-fold); only 2D2/Th mice exhibited a very strong 10.6-fold increase in the DNase activity of IgGs during the development of EAE. Free histones in the blood are cytotoxic and stimulate the development of autoimmune diseases. Only in 2D2/Th mice, during different periods of EAE development, was a sharp increase in the anti-antibody activity in the hydrolysis of some histones observed. Full article

Pork supply prediction is a challenging task of significant importance for pig producers and administrators, as it aids decision-making and maintains the pork supply–demand balance. Previous studies failed to consider impact factors like the month-age transfer principle of pigs, epidemic factors, and the simultaneous import and export volumes of pork, leading to the absence of a quantitative prediction model for pork supply. In this background, we proposed a novel quantitative prediction model of pork supply that incorporates pork production and pork import/export volumes. First, a prediction model for pork production that takes into account the month-age transfer principle of pigs and epidemic factors was presented, along with a recursive model of the pig-herd system. A novel method based on a modified self-organizing migrating algorithm (MSOMA) was proposed for calculating the quantity of monthly newly retained sows (NRS). Furthermore, the pork-production prediction model considered the epidemic factor as a random disturbance term (RDT), and a prediction method based on MSOMA and a back-propagation neural network (MSOMA-BPNN) was introduced to predict such disturbance terms. Second, the proposed MSOMA-BPNN was employed to predict pork import and export volumes. The pork supply was subsequently determined based on the predicted pork production, as well as the pork import and export volumes. The proposed pork supply prediction model was applied to forecast China’s pork supply from 2010 to 2023. The results validate the high effectiveness and reliability of the proposed model, providing valuable insights for decision makers. The empirical results demonstrate that the proposed model is a promising and effective tool for predicting the pork supply. To our knowledge, this is a novel tool for pork supply prediction, considering the pig-herd system and pork import and export volumes from a systemic perspective. These features allow for consideration of the scientific formulation of a pig production plan, the establishment of early warning mechanisms to deal with epidemic situations and emergencies, and the regulation of pork supply and demand balance. Full article