Polyphenol-Based Nanomaterials: Progress and Challenges
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 36
Special Issue Editors
Interests: valorization of renewable polyphenols; biocatalysis; photocatalysis; organic chemistry; nanotechnology; cascade synthesis; green chemistry; natural substances
Special Issues, Collections and Topics in MDPI journals
Interests: lignin nanoparticles; cosmetic applications; sustainable catalysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue aims to explore the latest trends in the design and implementation of innovative strategies for the preparation and modification of multifunctional polyphenolic compounds, with a particular emphasis on the use of lignin nanoparticles to prepare nanosized ones. Moreover, its scope comprehends investigating their pharmacological effects and their versatile applications, including medical functions. It intends to focus on the development of novel strategies for producing green and sustainable nanomaterials based on polyphenols. Nanomanipulation of pristine polyphenols allows for the protection of them from early degradation, the enhancement of their solubility, bioavailability, and their several properties, including pharmacological ones, and especially their antioxidant effects. Additionally, studies on their use and that of pristine or modified polyphenolic small molecules and macromolecules in biocatalytic, photocatalytic synthesis, and electrocatalysis processes, as well as to treat diseases, especially those caused by oxidative stress, such as neurodegenerative ones, are welcome.
Particularly, polyphenolic nanostructures, thanks to advanced properties such as J-type π-π interactions that enhance the electrochemical process, open new frontiers in green chemistry and enable advanced applications in green catalysis and photocatalysis. On the other hand, polyphenolic materials, due to their multitarget health properties, mainly based on their strong radical scavenging effects, are very promising materials to prevent and treat the development of multifactorial chronic neurodegenerative disorders. Also, this Special Issue examines the design and synthesis of innovative nanoparticles and their advanced functionalization strategies, such as enzyme immobilization.
This Special Issue invites research to contribute with work that addresses, but is not limited to, the following topics:
- The development of new catalytic and biocatalytic processes in organic chemistry. Innovative techniques for enzyme immobilization and their applications.
- The synthesis and application of polyphenol-based biomimetic reagents for material functionalization.
- The preparation and characterization of polyphenolic materials with bioactive functionalities exploitable for treating multifactorial human disorders.
- Sustainable methodologies for the synthesis of natural bioactive organic compounds.
- Studies of multitarget pharmacological effects of pristine or modified polyphenolic small molecules and macromolecules and their biomedical applications.
We look forward to receiving your contributions to this collection, which aims to consolidate knowledge and promote innovation in the field of organic chemistry applied to bioactive materials.
Dr. Eliana Capecchi
Dr. Davide Piccinino
Guest Editors
Manuscript Submission Information
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Keywords
- polyphenolic small molecules
- polyphenolic macromolecules
- organic chemistry
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