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Elisabeth Sparkle is a former A-lister past her prime who is suddenly fired from her fitness TV show.
She is then drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection and she is reborn -- temporarily -- as the gorgeous, twentysomething Sue.
The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?