Sean Baker said he was already a fan of Mikey Madison's work after seeing her in Once Upon a Time... in Hollywood (2019), to the point where he rewatched it just to watch her scenes. While this film was in early development, he saw Madison in Scream (2022) with his wife/longtime producer Samantha Quan. As they were walking out of the theater, he immediately wanted to contact her agent for this part.
According to Sean Baker, one scene where the characters walk into Tatiana Grill in Brighton Beach and interact with a dinner party was completely improvised and shot in a guerrilla fashion. Karren Karagulian, Baker, and cinematographer Drew Daniels crash a dinner party to film scenes of Toros asking the guests where Ivan is, with Daniels mounting a 35mm camera to shoot the scene the entire time.
According to Sean Baker at a Q and A to Australian audiences, Lindsey Normington who plays Anora's rival 'Diamond', has a background as an exotic dancer, and provided a great deal of consultation during the filming of the movie.
At the Cannes Film Festival press conference, Mikey Madison said that director Sean Baker would act out different sex positions with his wife, producer Samantha Quan, to demonstrate to the actors what he wanted them to do.